Protein Info for Psyr_4210 in Pseudomonas syringae pv. syringae B728a

Annotation: sodium/proton antiporter, NhaA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 53 to 79 (27 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 213 to 244 (32 residues), see Phobius details amino acids 264 to 285 (22 residues), see Phobius details amino acids 296 to 322 (27 residues), see Phobius details amino acids 334 to 356 (23 residues), see Phobius details amino acids 368 to 389 (22 residues), see Phobius details PF06965: Na_H_antiport_1" amino acids 19 to 385 (367 residues), 489.7 bits, see alignment E=2.6e-151 TIGR00773: Na+/H+ antiporter NhaA" amino acids 20 to 384 (365 residues), 463.6 bits, see alignment E=2.4e-143

Best Hits

Swiss-Prot: 100% identical to NHAA2_PSEU2: Na(+)/H(+) antiporter NhaA 2 (nhaA2) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K03313, Na+:H+ antiporter, NhaA family (inferred from 100% identity to psb:Psyr_4210)

MetaCyc: 58% identical to Na+:H+ antiporter NhaA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-129; TRANS-RXN-292

Predicted SEED Role

"Na+/H+ antiporter NhaA type" in subsystem Na(+) H(+) antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZNN2 at UniProt or InterPro

Protein Sequence (392 amino acids)

>Psyr_4210 sodium/proton antiporter, NhaA family (Pseudomonas syringae pv. syringae B728a)
MHKPTPRTESPNALAFITRFFAAESAGGLVLMAAALAALIVANSPLGDSYFAALHAVFAG
LSVSHWINDGLMAIFFMLVGLEIKREVLAGQLASWSQRALPGFAALGGMLVPALIYVAFN
WGRPDTIGGWAIPAATDIAFALGVLSLLGKRVPLSLKIFLSALAILDDLGAVLIIALFYT
SDLSIPMLLAALGSIAMLVALNRLGVKKLLPYLIVGALLWFFMLQSGIHATLAGVALALC
IPLGKPDEEARSPLLHLEEKLHPWVAFAVVPIFGFANAGVSLSGITADTLVDPVPLGVAL
GLLVGKQVGIFAMAALAIRAGLARLPDGSNWGQLYGVAALCGIGFTMSLFIGALAFPGAP
ELVDEVKVGVLIGSVLSAVLGVVVLRRFAQRG