Protein Info for Psyr_4196 in Pseudomonas syringae pv. syringae B728a

Annotation: GrpE protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 PF01025: GrpE" amino acids 12 to 174 (163 residues), 176.8 bits, see alignment E=1.4e-56

Best Hits

Swiss-Prot: 100% identical to GRPE_PSEU2: Protein GrpE (grpE) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K03687, molecular chaperone GrpE (inferred from 98% identity to psp:PSPPH_4207)

Predicted SEED Role

"Heat shock protein GrpE" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZNP6 at UniProt or InterPro

Protein Sequence (187 amino acids)

>Psyr_4196 GrpE protein (Pseudomonas syringae pv. syringae B728a)
MADEQNLDAQAQDQAAEAGAGDELTTRVQVLEEQLAAAQDQSLRVAADLQNVRRRAEQDV
EKAHKFALEKFAGDLLPIIDSLERGLDLSSPDDESIRPMREGIELTLKMFQDTLKRYQLE
AIDPHGQPFSADQHQAMAMQESADVEPNTVLKVFQKGYQLNGRLLRPAMVVVSKAPSPAT
PSINEQA