Protein Info for Psyr_3858 in Pseudomonas syringae pv. syringae B728a

Annotation: Nucleoside-specific channel-forming protein, Tsx

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF03502: Channel_Tsx" amino acids 64 to 319 (256 residues), 233.1 bits, see alignment E=2.1e-73

Best Hits

Swiss-Prot: 57% identical to TSX_SALTI: Nucleoside-specific channel-forming protein Tsx (tsx) from Salmonella typhi

KEGG orthology group: K05517, nucleoside-specific channel-forming protein (inferred from 100% identity to psb:Psyr_3858)

MetaCyc: 52% identical to nucleoside-specific channel-forming protein Tsx (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-468

Predicted SEED Role

"Nucleoside-specific channel-forming protein Tsx precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZPN4 at UniProt or InterPro

Protein Sequence (319 amino acids)

>Psyr_3858 Nucleoside-specific channel-forming protein, Tsx (Pseudomonas syringae pv. syringae B728a)
MPQPPFTRPAMPSRFLMPLLFAAAAALPCTSVLAAPATAEDSAQGEALSPPASPKEGKGA
YFSDWFNQDLTLIGSKDISFGPKPNDDIYLEYEYFGRKGPFELYGYVDVPKILGIGNDND
KGVWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYVAFDWIYDHGSNTANRANTLYSG
LGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQLKYIVPISTFDNGASLTYIG
FTNFDFGSDLKNDPARTGNSTVATNVLLYAFTHLRFTLVGRYFHNGGNWQDGSELNFGDG
NFRARSDGWGYYAGVGYQF