Protein Info for Psyr_3113 in Pseudomonas syringae pv. syringae B728a

Annotation: N-acylglucosamine 2-epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 48% identical to SQUS_ECOLI: Sulfoquinovose isomerase (yihS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_3113)

MetaCyc: 48% identical to sulfoquinovose isomerase (Escherichia coli K-12 substr. MG1655)
Mannose isomerase. [EC: 5.3.1.7]; RXN-15296 [EC: 5.3.1.7, 5.3.1.31]

Predicted SEED Role

"N-acylglucosamine 2-epimerase (EC 5.1.3.8)" in subsystem Sialic Acid Metabolism (EC 5.1.3.8)

MetaCyc Pathways

N-acetylneuraminate and N-acetylmannosamine degradation II (1/3 steps found)
sulfoquinovose degradation III (1/4 steps found)
sulfoquinovose degradation I (1/5 steps found)
sulfoquinovose degradation VI (1/5 steps found)
sulfoquinovose degradation V (1/7 steps found)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.8 or 5.3.1.31 or 5.3.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZRS7 at UniProt or InterPro

Protein Sequence (414 amino acids)

>Psyr_3113 N-acylglucosamine 2-epimerase (Pseudomonas syringae pv. syringae B728a)
MNNNNQTFSSWLRSPAHHQWLALEGNRLLTFAKASRLDNGFGSLDDYGRLMVGATAGTMN
TARMTHCFAMAHAQGIPGCAALVDHGIAALRGPLHDAEHGGWFSAALEDGGKTDKQAYLH
AFVALAASSAVVAGRPGAQALLSDAIQVIQTHFWSEQEGAMRESFARDWSSEESYRGANS
NMHSTEAFLALADVTGDAQWLDRALSIVERVIHEHAGANNFQVIEHFTQDWQPLADYNRE
NPADGFRPFGTTPGHAFEWSRLVLHLEAARRQAGRANPEWLLDDARQLFANACRYGWDVD
GAAGIVYTLDWQNEPVVRHRLHWTHCEAAAAAAALLQRTGEQQYEDWYRCFWEFNETLFI
DHEHGSWRHELNERNEPSADVWPGKPDLYHAYQATLLPVLPLAPSLASALAGLE