Protein Info for Psyr_2445 in Pseudomonas syringae pv. syringae B728a

Annotation: multi-sensor hybrid histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1172 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details PF05227: CHASE3" amino acids 45 to 179 (135 residues), 121.5 bits, see alignment E=9e-39 PF13185: GAF_2" amino acids 253 to 388 (136 residues), 62.1 bits, see alignment E=2.3e-20 PF01590: GAF" amino acids 257 to 387 (131 residues), 49.9 bits, see alignment E=1.8e-16 PF00512: HisKA" amino acids 494 to 561 (68 residues), 63.7 bits, see alignment 4.7e-21 PF02518: HATPase_c" amino acids 609 to 718 (110 residues), 98.7 bits, see alignment E=9.7e-32 PF00072: Response_reg" amino acids 782 to 888 (107 residues), 56 bits, see alignment E=1.5e-18 amino acids 904 to 1013 (110 residues), 54.8 bits, see alignment E=3.5e-18 amino acids 1050 to 1162 (113 residues), 97.2 bits, see alignment E=2.4e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2445)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZTN8 at UniProt or InterPro

Protein Sequence (1172 amino acids)

>Psyr_2445 multi-sensor hybrid histidine kinase (Pseudomonas syringae pv. syringae B728a)
MNRTSVVDEQRFRKLLGRNVGLPLGVGVLSAVFFILLISYLLTAIQWVEHTDRVINNTNR
SMKLSIDMETGMRGFLLTGDQHFLDPYEVAKPLLLAELQGLEKLVDDNPTQLDRFRRLST
LQQEWNAFAQEMITLRRTNGDYQTPVLAGRGKRITDQIRTEYDQAVEMEQQLRLTRNAEV
TRSTILSVTLYLIFVVVVSAILAYIGRRDLLSLSNTYSENLRLQEVNTERLQKVAWLRNG
QSELAEQVLGQLTLNMLGRNILQFLTQYLGASVAAVYIRQDHGGLTRAASYGFSREQEQQ
DQTIHSDEGIVGQAAQQDRIITLDELPDNYFKVASGLGEGSPRSVVVVPTSNDDQVNGVI
ELGFLRALTERDIEFLELVADNVGTSIEAARYRQRLQEVLAETQQLNEELQVQQEELRTA
NEELEEQSRILKESQAHLETQQAELEQTNEQLADQSQALAEQRDALDRNNEELNIAQAEL
QARADELQRASKYKSEFLANMSHELRTPLNSSLILAKLLAENPGENLTAEQVKFAESIYS
AGNDLLNLINDILDISKVEAGKLEMRPENSSVSRLVEGLRTLFQPLAAEKKLAFTVDIQA
GAPTMLFTDRQRLEQILKNLLSNAIKFTEAGSVSMVVSRQPGAGIAFIVRDSGIGIAEEH
QQGIFEAFRQADGTTNRRYGGTGLGLSISRDLAALLGGSISVTSAPGQGSIFSLVLPEHY
VEQDDREPGSDLPIVSAPAALQPYAPVLPVIAQPVPAPVPMDTPVPVFDDDRDKAPFQRR
CILVIEDEVRFAQILYDLAHELGYDCLVAHAADDGFNLASRYTPDAILLDMRLPDHSGLT
VLQRLKELAPTRHIPVHVISVEDRQEAALHMGAIGYAVKPTTREELKDVFAKLEAKLTQK
VKRILLVEDDALQRDSIARLIGDDDIEITAVGFAQEALDLLRDHVYDCMIIDLKLPDMLG
NELLKRMSMEDICAFPPVIVYTGRNMTRDEEAELMKYSRSIIIKGARSPERLLDEVTLFL
HKVESQLSNERQKMLKTARSRDKVFEARKILVVDDDVRNIFALTSALEHKGAVVEIARNG
LEAIARLNEVEDIDLVLMDVMMPEMDGYEATIEIRKDPRWRKLPIIAVTAKAMKDDQERC
LQAGSNDYLAKPIDLDRLFSLIRVWLPKMERI