Protein Info for Psyr_2374 in Pseudomonas syringae pv. syringae B728a

Annotation: ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 14 to 36 (23 residues), see Phobius details amino acids 142 to 167 (26 residues), see Phobius details PF00512: HisKA" amino acids 223 to 282 (60 residues), 36.9 bits, see alignment E=3.1e-13 PF02518: HATPase_c" amino acids 333 to 425 (93 residues), 51.5 bits, see alignment E=1.3e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2374)

Predicted SEED Role

"two-component system sensor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZTV9 at UniProt or InterPro

Protein Sequence (434 amino acids)

>Psyr_2374 ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal (Pseudomonas syringae pv. syringae B728a)
MIDFARRRGSLHRLVSVIILGFGLLMTTGLTTLAFMSQDLVDHPIWKDLLETATANTLAD
DVLPAAQKDARIQVWKLSGSTPAAGMPPSLAALAPGYYSEGDLDRQDADNGDRDYAVLVT
SLGRERLIAAIDISDLEREQNFIALVGAMFLVLNLILIIAVIAWLYVRLHLPVQGLALGM
KQLDPERPAQRLPVHYAQEELKDIACGINAHLERVEQFMARERALLDQASHEFRTPIAVI
SGALDILARQKLPPRAAPPLQRMRATVENLTEIMVALLYLSREPLTSNRDDPIELDRLLP
GLVKDHEHLLDGKPVKFSVQIHQTLTLHVPEAMLRIAVGNLLRNAADNTYDGTIAVRLKD
DVLSVTDSGEGFDTEQASRHYLSLLRNPIRTGSGKGLGLFLVRRICERFQWTLTLESMPT
LGTRAGLDFRSRPV