Protein Info for Psyr_2362 in Pseudomonas syringae pv. syringae B728a
Annotation: Silent information regulator protein Sir2
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 87% identical to NPD3_PSESM: NAD-dependent protein deacetylase 3 (cobB3) from Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2362)Predicted SEED Role
"NAD-dependent protein deacetylase of SIR2 family" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Redox-dependent regulation of nucleus processes
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q4ZTX1 at UniProt or InterPro
Protein Sequence (281 amino acids)
>Psyr_2362 Silent information regulator protein Sir2 (Pseudomonas syringae pv. syringae B728a) MLDSPIRDLLDTLCQVMADKPFLVVTGAGISTASGIPDYRDKNGVRRGKQPMMYQEFLGN PAARQRYWARAMLGWPRIRAAQANAAHLALAALQAEHAITGLITQNVDALHTQAGSRDVI ELHGSLHRVLCLDCQQRSDRAGIQEQMLAHNLYLIGVHATQAPDGDTLLDPAFEASFEVP RCPHCGGDRLKPDVVFFGENVAAQTAARATQSVEDAEGLLVVGTSLMAWSAFRLCKAMAE QGKPVIAINHGKTRADELLEMKIEASCEQALPWLAEQLVSP