Protein Info for Psyr_2313 in Pseudomonas syringae pv. syringae B728a

Annotation: peptidoglycan glycosyltransferase / cell elongation-specific peptidoglycan D,D-transpeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details TIGR03423: penicillin-binding protein 2" amino acids 20 to 606 (587 residues), 748.4 bits, see alignment E=2.8e-229 PF03717: PBP_dimer" amino acids 63 to 234 (172 residues), 153 bits, see alignment E=1.2e-48 PF00905: Transpeptidase" amino acids 267 to 603 (337 residues), 233.6 bits, see alignment E=3e-73

Best Hits

KEGG orthology group: K05515, penicillin-binding protein 2 (inferred from 100% identity to psb:Psyr_2313)

Predicted SEED Role

"Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Flagellum in Campylobacter or Peptidoglycan Biosynthesis (EC 2.4.1.129)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZU16 at UniProt or InterPro

Protein Sequence (629 amino acids)

>Psyr_2313 peptidoglycan glycosyltransferase / cell elongation-specific peptidoglycan D,D-transpeptidase (Pseudomonas syringae pv. syringae B728a)
MPNPIPLKDHEKETRLVNQRLIACAVLVGLLAACLVARMYFLQVTEFDYHSTISENNRVH
VLPIPPERGLIFDRNGEVLADNRPSFNLTLTRERAGDWHKVIDELMTLLELPDEDRILFD
KELKQVRHPFEPATLLYELTEEQIAILAVNQYLLPGVDVAAQFVRHYPLGAHFAHSIGYV
GRINEKEAAHLDNEYRGTQSIGKTGVERFYESELHGHVGYEEVETNAQGRVLRVLKHTDP
VPGKNITLTLDAHLQAAAENALGDRRGSVVALDPETGDVLAMVSKPSFDPNLFVTGISFK
QYAALRDSIDRPLFNRVLRGLYAPGSTVKPEVAIAGLDSGVVTASTKVFDPGYFQLPDFD
HKYRNWNHSGDGWVDMDTAIMRSNDTYFYTVAHKLGIDRLHDYMTMFGIGQKVSLDMFEE
SAGLMPSREWKRATRRQAWFPGETVILGIGQGYMQVTPLQLAQATSLIASKGVWHRPHLA
MEVGDTAPVDEHPMPNIVLHDPNEWNQVNTGMQMVMHDPRGIARDAAKGAQYRIAGKSGT
AQVVAIKQGERYNRLKTLERNRDNALFVGFAPADHPKIVVSVTIENGEAGGRVAGPVVRE
ILDAWLLDSEGKLKPEYATPAKAPGNPHA