Protein Info for Psyr_2246 in Pseudomonas syringae pv. syringae B728a

Annotation: Histidine kinase, HAMP region:Cache:Bacterial chemotaxis sensory transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 278 to 301 (24 residues), see Phobius details PF02743: dCache_1" amino acids 36 to 259 (224 residues), 95.3 bits, see alignment E=6.2e-31 PF00672: HAMP" amino acids 295 to 348 (54 residues), 59.1 bits, see alignment 6.5e-20 PF00015: MCPsignal" amino acids 412 to 594 (183 residues), 150.8 bits, see alignment E=5.3e-48

Best Hits

Swiss-Prot: 63% identical to PCTC_PSEAE: Methyl-accepting chemotaxis protein PctC (pctC) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to psb:Psyr_2246)

Predicted SEED Role

"Chemotactic transducer"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZU83 at UniProt or InterPro

Protein Sequence (629 amino acids)

>Psyr_2246 Histidine kinase, HAMP region:Cache:Bacterial chemotaxis sensory transducer (Pseudomonas syringae pv. syringae B728a)
MKSLGFSKKILLAAALIVVVAFSVFIVVNDYRQRQSLKSSVKSELQQLGTLTTQNIQTWL
ESRMQLLQSMSQQIAADGKELPQLQRAIGLPAYSESFQLSYFGSTEGVMFSVPSANRPAD
YDPRARGWYKAAQNAPGTIVTEPYIAASSGKLVMTMATPVKFQNQFVGVAGADIALDNVT
KIINSLNFDGHGYAFLVSADGKILVHPDSKLVLKNISEAYPTNTPKITTGVTEIDSGKNP
EIISFTPVQGVSTANWYVALVLEQDSAYAMLAEFRASAITAMVVVVVVIILLLGLLIRVL
MQPLHQMGRAMRDIADGEGDLTKRLAITSQDEFGELAESFNRFVERIHTSIREVASTAAQ
LGEVATRVVKVSNASMGNSDQQANRTESVAAAINELGAAAQEIAQNAARTSQQSSDASGL
ASDGQNVVQQTIKAMNELSGKISESCVNIESLNGKTANIGQILEVITSISQQTNLLALNA
AIEAARAGEAGRGFAVVADEVRNLAHRTQDSAQQVQTMIEELQVGARDAVTNMTESQRQS
EDSVGIANLAGERLGSVTRRIEEINGMNQSVAAATEEQTSVVESINVDITHINTLNQLGV
DNLRQTLEACNSLEEQAARLQQLVGSFRI