Protein Info for Psyr_2240 in Pseudomonas syringae pv. syringae B728a

Annotation: Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 1 to 178 (178 residues), 28.6 bits, see alignment E=1.5e-10 PF00672: HAMP" amino acids 204 to 256 (53 residues), 29.4 bits, see alignment 1.3e-10 PF00015: MCPsignal" amino acids 320 to 503 (184 residues), 161.9 bits, see alignment E=2e-51

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to psb:Psyr_2240)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZU89 at UniProt or InterPro

Protein Sequence (537 amino acids)

>Psyr_2240 Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer (Pseudomonas syringae pv. syringae B728a)
MSIKLRLFLLIGTSVLTVMIISLVNYLGNTRMEAAMLDSEVSMAALGNHLEADMMHDALR
ADVLSAMLFGLGRSNSTRDEVQTSLKEHAALFRKVVSDNLQLPLTDAIKAELSRIKPSLD
AYISAGERIVGLAIDSPDRAQQELGTFSSAFTQLEGQMSTLSDLIEDNSKASGERTRQTT
RSANLTLAVVLSISILLLLVQGHWVTRSIMIPLASASRIADSIAHGNLSEPIAESRGRDE
ASMLIRSLAIMQRDLRSMIEVVRSNANDVSGMSRQLSSGCHEVADSSRQQSSAAGTMSAA
TSEMTASIEEITRHAGQALEMASQAESLAKNGGRVIHQVVSDMDSIARSAQQSAQVIRTL
DKDSEGIFNIIQVIKGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGRTSAST
QEITAMVARIQQSTREAVTSMEAGVAQVDKGMAVTAEVERAISDILAATLSTTQLVNDIT
RTIGEQSLASNEIAHQVEMIASMSEGNSRVIGQTASTTDELSVMAGQLSQSVDRFQL