Protein Info for Psyr_2232 in Pseudomonas syringae pv. syringae B728a

Annotation: Major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 transmembrane" amino acids 59 to 82 (24 residues), see Phobius details amino acids 91 to 113 (23 residues), see Phobius details amino acids 115 to 115 (1 residues), see Phobius details amino acids 122 to 144 (23 residues), see Phobius details amino acids 157 to 176 (20 residues), see Phobius details amino acids 182 to 201 (20 residues), see Phobius details amino acids 235 to 256 (22 residues), see Phobius details amino acids 268 to 290 (23 residues), see Phobius details amino acids 302 to 319 (18 residues), see Phobius details amino acids 325 to 348 (24 residues), see Phobius details amino acids 360 to 382 (23 residues), see Phobius details amino acids 389 to 411 (23 residues), see Phobius details PF12832: MFS_1_like" amino acids 28 to 393 (366 residues), 55.4 bits, see alignment E=8.4e-19 PF07690: MFS_1" amino acids 33 to 278 (246 residues), 96.9 bits, see alignment E=1.9e-31 amino acids 276 to 420 (145 residues), 58.3 bits, see alignment E=9.8e-20 PF00083: Sugar_tr" amino acids 268 to 414 (147 residues), 40.1 bits, see alignment E=3.4e-14

Best Hits

Swiss-Prot: 56% identical to Y2456_MYCTO: Uncharacterized MFS-type transporter MT2531 (MT2531) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2232)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZU97 at UniProt or InterPro

Protein Sequence (432 amino acids)

>Psyr_2232 Major facilitator superfamily (Pseudomonas syringae pv. syringae B728a)
MTRLPGVGRITGISLLVSHADRRNTLSLDSLNFFLADVRDGLGPYLAIYLLAVHKWDPAS
IGVVMTIAGIAGLLTQTPAGALIDRTPYKRAMIGVAALLVTLSCLILPFTSSFSVVALTQ
ALSSIAASVFAPAIAAISLGITGPKAFTRRTGRNETFNHAGNACAALLAGGFAYLFGPIA
VFYLMAAMALASIVAVSFVSADAIDHDVARGFDASHDVSGHQPSGLSALLSNKPLLMFGI
CCALFHLANAAMLPLVSQKLSQINMQMATPLTSACIVAAQLVMVPAALLVGMKADVWGRK
PLLLAGFLFLPIRGVLYTFSDDPYWLVAVQMLDGIGAGLFGALFPLMVKDLTQGSGRFNV
SLGALSTLFGLGAALSNSLAGFVVHAAGYSAAFLTLAGVAAVAFCLLWLAVPETLSRSHN
EPELKADNAVGA