Protein Info for Psyr_2220 in Pseudomonas syringae pv. syringae B728a

Annotation: Histidine kinase, HAMP region:Cache:Bacterial chemotaxis sensory transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 25 to 25 (1 residues), see Phobius details amino acids 291 to 316 (26 residues), see Phobius details PF02743: dCache_1" amino acids 48 to 273 (226 residues), 92.2 bits, see alignment E=7.1e-30 PF17201: Cache_3-Cache_2" amino acids 188 to 291 (104 residues), 28 bits, see alignment E=2.8e-10 PF00672: HAMP" amino acids 313 to 365 (53 residues), 30.4 bits, see alignment 8.1e-11 PF00015: MCPsignal" amino acids 428 to 610 (183 residues), 141.6 bits, see alignment E=4.7e-45

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to psb:Psyr_2220)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZUA9 at UniProt or InterPro

Protein Sequence (646 amino acids)

>Psyr_2220 Histidine kinase, HAMP region:Cache:Bacterial chemotaxis sensory transducer (Pseudomonas syringae pv. syringae B728a)
MNIKQKLTWAFAVIACLPILVVAAIVVVNLRDKATSDFVDSSAREIRQVDNAMQLFFDGI
TQNVNYIAAHPLIAGASDDFRNYMGATPPPQSENDRQATELFASIAKAHPAYSYVSYGLI
NGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAYYWANDDAVLVSTIRAIPNKL
GNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDG
FSELAKTASGLVEVTLNGERYMANVYSSEQLGWNFIGLIKQDEVMASATRLTWLIGIIAA
VLAVVFAIVGASFARVIVRPIHSVSSGLEGIAGGEGDLTQNLAVRGKDETAQLAGWFNKF
LTAIRSLIQHIGQAAGKILEASHSSTRVSNDMAEAAGRQREAVDMVSTAFHEMVATSNEV
ARSCSQAADSADNGQQQAREGQRQIDDAVRSVDQLSEELTRSAKDMTQLEKDSAGIQSIL
NTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTSDSTAEIDSLLGNLA
KRTASVAQQMHASLDVSQQSVTKIGQARSSFGQIRESVDVIRDMNTQIATAAEEQHQVAE
DINRHISQIHGDAQLIAQLSDSARADSRSLEMLSSELDGLVRKFKT