Protein Info for Psyr_2116 in Pseudomonas syringae pv. syringae B728a

Annotation: Deoxyguanosinetriphosphate triphosphohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01353: putative dGTPase
  • amino acids 24 to 435 (412 residues), 315.6 bits, E=3.6e-98
• PF01966: HD
  • amino acids 61 to 124 (64 residues), 26.7 bits, E=3e-10

Best Hits

Swiss-Prot: 87% identical to DGTL2_PSEA8: Deoxyguanosinetriphosphate triphosphohydrolase-like protein (PLES_20171) from Pseudomonas aeruginosa (strain LESB58)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 100% identity to psb:Psyr_2116)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

See Q4ZUL3 at UniProt or InterPro

Protein Sequence (443 amino acids)

>Psyr_2116 Deoxyguanosinetriphosphate triphosphohydrolase (Pseudomonas syringae pv. syringae B728a)
MDWQTLLNRERLGKTLHSPEELGRSPFHKDHDRIIFSGAFRRLGRKTQVHPVSSNDHIHT
RLTHSLEVSCVGRSLGMRVGETLRSALPDWCDPSDLGMVVQSACLAHDIGNPPFGHSGED
AIRNWFNQAAGRGWLDAMSETERNDFLNFEGNAQGFRVLTQLEYHQFDGGTRLTYATLGT
YLKYPWTARHADSLGYKKHKFGCYQSELPILEQIAGKLGLPQLEDQRWARHPLVYLMEAA
DDICYALIDLEDGLEMDLLNYAEVESLLLGLVGDDLPETYRQLGPGDSRRRKLAILRGKA
IEHLTNAAARAFVEQQDALLAGTLPGDLVEHMHGPAKRCVLNAKDMARKKIFQDKRKTLH
EIGAYTTLEILLNAFCGAAVEQFGGRTPSFKHRRILDLLGNSAPDPKAPLHTSFLRMIDF
IAGMTDSYASEMAREMTGRSGQI