Protein Info for Psyr_2031 in Pseudomonas syringae pv. syringae B728a

Annotation: ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details PF00672: HAMP" amino acids 86 to 136 (51 residues), 42.4 bits, see alignment 1.1e-14 PF00512: HisKA" amino acids 140 to 188 (49 residues), 29 bits, see alignment 1.3e-10 PF02518: HATPase_c" amino acids 238 to 342 (105 residues), 88.4 bits, see alignment E=6.5e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2031)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZUU8 at UniProt or InterPro

Protein Sequence (344 amino acids)

>Psyr_2031 ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal (Pseudomonas syringae pv. syringae B728a)
MIRRFDTLFARLFGGALLAILLAHLLAFIWFTQYGMRPPPPTPNEFNAEHGQFDQRPMHR
PPILGGPLILLFFQFITLIIAAWYGAKALSRPVRSLSEAAERLSEDLDSPPLEISGPQEA
RQAAQTFNLMQRKIREQMQQRGRMLAAVSHDLRTPLSRLKLRVEQIEEPRLHGQMTQDLN
DMISMLDATLAYLNEHRRSEGLQQFDLQALIESQAENAQDNGDDVQYEGQCKPLKTQPMA
LRSCLQNLVDNALRYAGSARIVIEDSADHVRISVVDHGPGIAPEFHETVFEPFFRLESSR
NRNSGGIGMGMSIAREAARRIGGELSLAQTPGGGLTAILVLPRL