Protein Info for Psyr_1705 in Pseudomonas syringae pv. syringae B728a
Annotation: Amino acid adenylation
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 2.3.1.39)
MetaCyc Pathways
- superpathway of fatty acids biosynthesis (E. coli) (51/53 steps found)
- superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
- superpathway of fatty acid biosynthesis I (E. coli) (15/16 steps found)
- fatty acid biosynthesis initiation (type II) (3/3 steps found)
- superpathway of fatty acid biosynthesis initiation (4/5 steps found)
- fatty acid biosynthesis initiation (mitochondria) (2/4 steps found)
- fatty acid biosynthesis initiation (plant mitochondria) (1/4 steps found)
- mycobactin biosynthesis (3/11 steps found)
- pederin biosynthesis (2/14 steps found)
- bryostatin biosynthesis (2/19 steps found)
- mupirocin biosynthesis (2/26 steps found)
- corallopyronin A biosynthesis (2/30 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.3.1.39
Use Curated BLAST to search for 2.3.1.39
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q4ZVR9 at UniProt or InterPro
Protein Sequence (4186 amino acids)
>Psyr_1705 Amino acid adenylation (Pseudomonas syringae pv. syringae B728a) MSQKKPVTSTTESAVRMPTPAAGGFLNLSPAQKSLWFMHQMEDASATYNVPFALRIDGAL DRAALERAVDSVYQRQSALRYRFPCIDGQPVIRLVDEQLLIRKVDLRAEPDSEAALKAFE QSEARYVFDLEHEALLRATLLHCATDEHVLLINVHHIVFDGWSMQIFLSEVASAYSALVR GSEVNAEPLNFDFGDYLSLSPSNAERAPDIDHWQRRLAGAPPVLPLPLDNKRPAVQRYAG QRCHFQVPEAVSDALKNLARECRVTPYMVGLAAFSVLLYRYTQEADLVIGSPMSNRQSSD LEGVIGFFVNTLPNRIDASGSPSFVELLKRVRASVLDTFEHAHVPFDQIVEAIQPPRSLS HAPVFQVLFDMANEDFSVELENLRTRVYTLDSCTAKYDLSLTLALTARGMSGAIEYDTAL LDERAVQGMIDSLLIIMEQVSRNPDGAIDDFSLLSCEAVEQALRLANHQPAAPQAPFAPF HQWFKRSAAQWGEADALVYENRRYSYAQLDAEARVLAGHLHAAGVRRGDRVAVVQRYGPE VIIALLAVHQVGGIYVPLAIDDARHADLLKDIEPRLVLTLSACQEQLRGYPCLVQDDLPQ ATGTLHENEFEGRNTQPEDIAYIIFTSGSTGRPKGVSVSHGSWVSLLQALEQTYGQTEPG VTGILQMANFTFDVFMSDVVRALAVGARLIMCPRQSLADPEQLYELITAERVTLLEFVPA VLRQMIRYLEETGRRLDTLRTLTCGADVWFVHEYRKMQTLCGPQTRVVSVYGVTEATCES ATFEPDAGWYDPERSLPIGGPLPNTSLYLVDATLNLVPRTVPGELLIGGGAVASGYMNRP ELNEKSFLTGSFSASGRFLPGVGEQRFYRTGDLCRHMRDGTIEFLGRSDNQVKIRGFRIE LGEVESVLADHPDVNECAVVTRQSPGAEAELIGYVQTRATAQQLNAYLGERLPGHMVPRL LVVLAALPLTANGKIDRKSLPEPDWTQDSRAYAAPRNSLEEQLVEDWQHLLNVPRVGIDD NFFESGGHSLLVTQVIAQIKKRFGVALSIANLFEGPTVAQVAEKIMLSMIQISQGASVAS RPAAIGRSSGIERQRLSFAQRRLWLTQHSEPGTAYNMPEICRLTGQLDIPALEGALNLLL ERHEVLRTHFTRELETFVDTQGVTQKEPLVVTSHADSARVPFRLQTIAREALTAALEREV HTPFVLDKELPIRALLLQTASDEHVLCLTLHHIAYDGWSSALLRQELAVFYRHLTQGERI TLSPLEAQYQDYAAWQRNQLETGAFTTQLDAWKASLQDLPPPLVLPVRSSPREGNPLAGD YVALTLPGDCSARLDQLCLRLQCTPAMVMHAAFALLLHRYTGQDDILIGMPFSGRDHDES TNLIGFFVNLLPLRLRLRGPLRVAQVIEQSRQALLAAEANQSVPIDYLAQVLNPQRLPGK HPFFQAGLVVQSTTAVPLSLPHVTSEEISLASTEVKLDLMLELRAVKGEGVSGVFKYRTS LFERSVISGMAGHFQCLLENMLANDEQTVAQVKMLSATEQQRLISQFNDTARDFGDGDVV SRFEQRVRQTPQAMALQLQQRCWTYAELDRLANGIAHALIKKGVQAGEHIGLFTGRHPYL VAGMLGILKARCAFVPLNPQDSMEGALGYMIKDAALHRVVGHRGLAHELAALGLETLLVD DFEGEQGEWSAPACQREPQDLAYILYTSGSTGQPKGVMVSQCNIDNTASAFARTLELTGQ SRQLQYFSPVFDGVCGEVFPVLISGATLVFAASEQLLPGPDLVTLLREQRITHLQITPTA LRLLPHAELAELKVIISAGEACPANVAQTWAAGRRFLNGYGPTETTVYASARDYWDERGA LVLRPLDNVRMYVLDRYLNPLPCGVPGELYIGGSGVAQGYLNLDERTAQAFLPDPYGVSP EARLYRTGDFVVRQFNGSLSYVGRIDNQVKIRGFRIELGDVETRLNAIAGLEQAVVVVKQ DDQGHKALVGYYVGKPSVAQVRAELARVLPAHSVPERLVCLPELPLSRTGKVDRKSLENR VDQRAQEGTAVGTPATLPAAVRPAGKRLHNTVRTIWQEVLDCQEIDSDDNFFDLGGHSLR IVETQKRLSELLQAPVAMTDLFEYPTLRGLVAHLERLHGPLPEVRQASEASPAIDPGNRT LAVVGMAGRFPGAADLSEFWQNITEGVESTLYFSDEVMLAHGVNPDLLERADFVKCGNRL EDVDKFDAEFFGFSPREAQLMDPQQRIFLQCAWAAMEAAGYGGALNDLRVGVFASASTSH YLLDHVYPRRQELQLENIQWLLGNGRDFMASRVAYKLNLAGPAITVETACSSSLVAVQMA CESLLRGESDMVIVGGASVEAQYYGYQAAPGSIISVDGHCRPFDAQASGTTGGSGCAVLV LKLADRAIEDRDHIHALIKGGAINNDGSSKVSYTAPSVHGQAQVVSAALDAANISADSIG YVEAHGTGTRLGDPVEVRALTQAYTSALPHFTPGFCALGSLKSNIGHLDAASGIAGLVKA ILAVQHNVLPASLNFTRANPEIDFSDSPFYVNTTSRPWPAAASPRRAGVSSFGIGGTNAH VIVEEPPQPSVRPHDDSERWYILPFSARSAAALDHQRRQLITCLQNPAADLRDIAFTLGE GRTRFAFRDSVVSQSIAGALHALQAPSSTALMERRQDRPIVFMFSGQGSQYAGMFKGLYD SEAVFRQTVDRCAVILQRYGVDILACLYPPAGSKTGDALSRTEIAQPALFVVEYACALLL QSRGIHPQALIGHSLGELVAACFAGVYSVEDSLKLVVERGRLMQRQAPGAMLAVGLSEAD CARFLEPGVELAAVNGPLQCVLAGDFEAIARVERQLAEEGLVGRVLDTSHAFHSRMMAPA AHALKAVVNGFSVQPPTIALVSNHNGGWFSIDSSSQSDYWASHLLETVRFSDGIGLLADE LEEPIFLEVGPGRALQSALKSYAEPLCVLGCTRHARDSRSDEAALAQGIASLWRQGARFG WAQATGCTDGARVPLPTYPFARDSHWIEAAGTASSAQHEAPLFLHWQRMNGNRRQFRLSL SPQLWLVDEHRVFEGRPVLSGTGCVELVRNAYARMEGVESIELSDVYFPTPLVLEDEQAS QRVLITFKDHAESTEFFLESVSDEGNGPQQRTMLHAQGFIKRHDRERSVPTALMQLQADH ADCLADEVEHAALNTRLGLFGPRWKCFRSIWLSEDEGLALLELDQAFAADVEHFALHPAL LDMATGFLSIMENRARRLPFHYQRLTIHAPLRSRLYSHARRVRSNVYDVQLFEVDSDGGV GALLAEVTGFTLREERVASEAQRTEPLDWCQAPAWRPALPPRSDSPLQGPWLVVMRGVAA DNSMLFSLPPDSVCIADAGDSGTAVATIARGDAQAYEQLFNTLAAQDALPSQIIYVAGQA QPTHGEHAAIGLFTDLMSLVQAYIPHAANTTVLSLVTEGACQVDDDEPVNSCVATLSGVV RTLAWELPQIQCRHFDLPLVNAAENETLLLQALQHIDPDQASPLASTLALRKQTFHEPCL RALQVSPPSQPFEEGGTYVVTGGLGGMGLALASHLAAKAKAVTLVLMSRSATVTDEVGQA LQALEQQGARIQHMAVDCADREAFTAALHQVRLQHGRISGAIHAAGVQASGLIQLSQATA WAQVMGSKVVGTDVLIEVLRQEPVDFIFLCSSLASVLGGLGQADYAAANAYLDARAQACR QEGIPVVSLNWDAWAQAGMRVAYDRAHPEQAPIDDVRGLTNAEGCQLFELALAQNTAQVI VSKAQDLQQLIEQLQRGGATSAGRATPLFDSGAERVAPRNAVEQEVAQLWQELLGGDMPG VLDNFFDLGGHSLLGSQLISRIRSRFQQCLTLAEFLDEPTIERIARSLGSGADDTPIDAD EAAVRYCLVPVQRNGEGRPFFCLPGMGGNVNQVLGLAKAMGTQRPFYGLQCLGLDGKAEP HLSVEDMAEHYIRCMKSVQAHGPYLLGGHSLGGKVAYEIARRLEARGDQVGLLALFDSAA PPYTQMQVPTDAQVLGSLLSIFGHYFDKPIKLSREELQALEHLDDEEKIRYLKDTLESHG LLDARGDEGSIRGLFNVYKAAAAFGMRYDPPKVALDASLVLFRAVDSMPSGINLPEIRDT DAWGWESFSAAKVRTVDVSGDHFTCLSVHARQIADVLIEQLAECDR