Protein Info for Psyr_1638 in Pseudomonas syringae pv. syringae B728a

Annotation: RNAse E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1120 TIGR00757: ribonuclease, Rne/Rng family" amino acids 29 to 438 (410 residues), 555 bits, see alignment E=5.5e-171 PF00575: S1" amino acids 52 to 131 (80 residues), 47.3 bits, see alignment 3.4e-16 PF10150: RNase_E_G" amino acids 135 to 404 (270 residues), 336.8 bits, see alignment E=1.5e-104 PF20833: RNase_E_G_Thio" amino acids 416 to 500 (85 residues), 111.3 bits, see alignment 2.9e-36

Best Hits

KEGG orthology group: K08300, ribonuclease E [EC: 3.1.26.12] (inferred from 76% identity to pfs:PFLU4714)

Predicted SEED Role

"Ribonuclease E (EC 3.1.26.12)" in subsystem RNA processing and degradation, bacterial or Ribosome biogenesis bacterial (EC 3.1.26.12)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZVY6 at UniProt or InterPro

Protein Sequence (1120 amino acids)

>Psyr_1638 RNAse E (Pseudomonas syringae pv. syringae B728a)
MCAERRFRQPGNRRYYMKRMLINATQPEELRVALVDGQRLYDLDIESGAREQKKANIYKG
RITRIEPSLEAAFVDFGSERHGFLPLKEISREYFKKAPEGRVNIKDVLSEGQEVIVQVEK
EERGNKGAALTTFISLAGRYLVLMPNNPRAGGISRRIEGEERNELREALNGLIAPADMGL
IVRTAGLGRSSEEMQWDLDYLLQLWTAIKEASLDRSAPFLIYQESNVIIRAIRDYLRQDI
GEVLIDSIEAQEEALTFIRQVMPQYASKIKLYEDSVPLFNRFQIESQIETAFQRVVELPS
GGSIVIDPTEALVSIDINSARATKGSDIEETALQTNLEAAEEIARQLRLRDIGGLIVIDF
IDMTPAKNQRAVEEKVRESLEADRARVQIGRISRFGLLEMSRQRLRPSLGESSGIVCPRC
NGTGIIRDVESLSLAILRLIEEEALKDRTAEVRAQVPIPVAAFLLNEKRNSITKIELRTR
ARIIILPNDQLETPHFEVQRLRDDSPEAHSSQTSYEIAAAAAEVEEIAPLAAATRTLVRQ
EAAVKTAPARANAPVPVEAAAPAPTPAPAPVAHEPSLFKGLVKSLVSLFATKEEPVAPVV
VEKPVAEQRPARNEERRNGRQQSRGRNNRRDEERKPREERAPREERAERAPREERAPREE
RAPREERTVREPREAREESTPREERPARTTRERKPREAREDRPVRELREPLDAAPAVSLA
REERPERAPREERQPRAPREERQPRAEQAAAAVSEEEEVLLNEEQTNNENQEGNDGSEGD
RPRRRSRGQRRRSNRRERQRDANGNVIEGSEENGNEEEGSATDLSAGLGFTAAASAASSV
ISAPAEADAHQQAERANSNAATADAEPVHQETAAEAPVTETSVAETPATEAPVAEKAQTV
AEPTVEAPAVEAPVADDAPVAQPAPEVEVQPAAVEAPAIAAQSELFEAPHAERVVPFKPT
PEPAPQAPVEAAAHEEVPATESSELPTPAPAAVVEPVALQEEPAPYVAPQPVVEEQAPAP
QEQAPAAEEAAPAPVVSSTGRAPNDPREVRRRKREEEARRQQEAAAASAPVVEAAPAAAE
AESAQPSPAAEEKTEEAATEQPAVKPQHEAEKENEPKPLV