Protein Info for Psyr_1571 in Pseudomonas syringae pv. syringae B728a

Annotation: Twin-arginine translocation pathway signal:Copper-resistance protein CopA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR01480: copper-resistance protein, CopA family" amino acids 3 to 591 (589 residues), 994.5 bits, see alignment E=1.6e-303 TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 5 to 32 (28 residues), 24.5 bits, see alignment (E = 2.5e-09) PF07732: Cu-oxidase_3" amino acids 52 to 163 (112 residues), 136.4 bits, see alignment E=7.5e-44 amino acids 504 to 590 (87 residues), 25.5 bits, see alignment E=1.8e-09 PF00394: Cu-oxidase" amino acids 172 to 345 (174 residues), 92.3 bits, see alignment E=5.4e-30 PF07731: Cu-oxidase_2" amino acids 474 to 591 (118 residues), 105.6 bits, see alignment E=2.8e-34

Best Hits

Swiss-Prot: 89% identical to COPA_PSESM: Copper resistance protein A homolog (copA) from Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_1571)

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZW53 at UniProt or InterPro

Protein Sequence (592 amino acids)

>Psyr_1571 Twin-arginine translocation pathway signal:Copper-resistance protein CopA (Pseudomonas syringae pv. syringae B728a)
MPTRTSRRTFVKGLAASGLLGGLGLWRSPAWAVANPGQPNGLSGTEFDLYIGETQVNITG
NAKTAQTINGGIPGPLLRWREGDTVTLRVKNRLDEATSIHWHGIILPANMDGVPGLSFDG
IAPDGMYVYRFKVRQHGTYWYHSHSGFQEQSGVYGPLVIDPKEPEPFEYDREHVIMLSDW
TDEEPVQLMKTLKKQSDYYNNNQRTVGDFINDVGEKGWSETTRDRWMWAQMRMDPTDLAD
VSGATYTYLMNGQAPNMNWTGLFKPGERIRLRLINGSAMTYFDVRIPGLKMTVVASDGLH
VKPVTVDELRIAVAETFDVIVEPAEGAYTLFAQSMDRTGYARGTLASRPGLQAAVPPLDP
RPLSSMDDMGMAGMEHGSMNHAAAPATHDMSGMDHSKMGHDAMPGMDHAQTPAQKTPTPQ
SHPESENNNPLVDMQAMSTSPKLDDPGIGLRGNGRRVLTYADLRSTFEDPDGREPSRTIE
LHLTGHMEKYAWSFDGVKFSDAKPLMLKYGERVRVVLVNDTMMTHPIHLHGMWSDLEDEN
GQFMVRKHTIDMPPGSRRSYRVTADALGRWAYHCHMLYHMEMGMFREVRVEE