Protein Info for Psyr_1139 in Pseudomonas syringae pv. syringae B728a

Annotation: Response regulator receiver:CheW-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01584: CheW" amino acids 12 to 144 (133 residues), 110.5 bits, see alignment E=5e-36 PF00072: Response_reg" amino acids 171 to 280 (110 residues), 51.9 bits, see alignment E=7.8e-18

Best Hits

KEGG orthology group: K03415, two-component system, chemotaxis family, response regulator CheV (inferred from 99% identity to psp:PSPPH_1207)

Predicted SEED Role

"Chemotaxis protein CheV (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZXC9 at UniProt or InterPro

Protein Sequence (298 amino acids)

>Psyr_1139 Response regulator receiver:CheW-like protein (Pseudomonas syringae pv. syringae B728a)
MSKNVRADSLSLLLFTLRSGKLMAINLLKVSEIIPCPPLTHLPESHPHVKGIATLRGSSL
SVIDLSRAIGERPLADPDGGCLIVTDVSRSKQGLHVQAVSKIVHCLTTDIRPPPYGSSSK
SFITGVTQVDGVLVQVLDIEKVIHGIAPAQIVVQSTELAKEDAELLSKARILVVDDSQVA
LQQSIITLRNLGLECHTARSAKEAIDVLLDLQGTARQINVVVSDIEMSEMDGYALTRTLR
DTPDFSDLYILLHTSLDSAMNSEKSQIAGANAVLTKFSSPELTKCLIEAARTVVAQGL