Protein Info for Psyr_0607 in Pseudomonas syringae pv. syringae B728a

Annotation: cystathionine beta-lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF01053: Cys_Met_Meta_PP" amino acids 27 to 385 (359 residues), 319.2 bits, see alignment E=2.9e-99 TIGR01324: cystathionine beta-lyase" amino acids 27 to 387 (361 residues), 405.9 bits, see alignment E=6.6e-126 PF00155: Aminotran_1_2" amino acids 43 to 228 (186 residues), 22.8 bits, see alignment E=4.9e-09

Best Hits

KEGG orthology group: K01760, cystathionine beta-lyase [EC: 4.4.1.8] (inferred from 100% identity to psb:Psyr_0607)

Predicted SEED Role

"Cystathionine beta-lyase (EC 4.4.1.8)" in subsystem Methionine Biosynthesis (EC 4.4.1.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.4.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZYU5 at UniProt or InterPro

Protein Sequence (388 amino acids)

>Psyr_0607 cystathionine beta-lyase (Pseudomonas syringae pv. syringae B728a)
MPQDKDPRAHTALSQRGRSAGSGPGIAVNPPVVRLSTVLFDSLESLRQAEIRTTGPERSL
TYGANGNPTAFALQDLISELEGAHGTCLYPTGLAAVAQMFQSFLRPGDHVLITESVYGPV
RRLAKTMLTAFDIQFDFYAADGSNVESLIKANTRMIYAEVPGSLTFDMCDLPALSQLCKA
RNLLLAVDNSWGSGVLYKPLALGADISLMALTKYVAGHSDVMMGSVSTTEAHWHTLKTMN
TAVGNTVSPDDAYLVLRGARSLAARMAMHERHALQIAQWLQAQPQVARVLYPALPDDPGH
AIWKRDFHGCNGLLSFEFNTADRQVLDRFTGALKLFGIGYSWGGFESLITEVEQHGPERG
AGPMLRLQVGLESPEDLIADLRNGFAAE