Protein Info for Psyr_0497 in Pseudomonas syringae pv. syringae B728a

Annotation: LamB/YcsF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03746: LamB_YcsF
  • amino acids 4 to 241 (238 residues), 340.2 bits, E=3.7e-106

Best Hits

Swiss-Prot: 72% identical to PXPA3_PSESM: 5-oxoprolinase subunit A 3 (pxpA3) from Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

KEGG orthology group: K07160, UPF0271 protein (inferred from 100% identity to psb:Psyr_0497)

MetaCyc: 41% identical to 5-oxoprolinase component A (Escherichia coli K-12 substr. MG1655)
5-oxoprolinase (ATP-hydrolyzing). [EC: 3.5.2.9]

Predicted SEED Role

"Lactam utilization protein LamB"

MetaCyc Pathways

• 5-oxo-L-proline metabolism (5/6 steps found)
• γ-glutamyl cycle (4/6 steps found)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.9

Sequence Analysis Tools

See Q4ZZ55 at UniProt or InterPro

Protein Sequence (254 amino acids)

>Psyr_0497 LamB/YcsF (Pseudomonas syringae pv. syringae B728a)
MPAIDLNSDLGESFGAWSMGDDEAILDVVSSANVACGFHAGDPAGILRTLEAAAARGVAI
GAHVAYPDLVGFGRRNMDIPSDQLTADVIYQIGALQGLARSAGTRVSYVKPHGALYNTIA
GDQRQAAAVIQALLRIDPALKLVCLANSPLLDWAREAGLSCVAEAFADRAYTAQGTLVSR
SRPGAVLHDAELIAERMLRLVREDVIEAEDGREISLQADSICVHGDSPGAVNIARILKNR
LHDAGVTVRAFNRG