Protein Info for Psyr_0452 in Pseudomonas syringae pv. syringae B728a

Annotation: HylII

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 transmembrane" amino acids 10 to 30 (21 residues), see Phobius details amino acids 38 to 56 (19 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 100 to 117 (18 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 183 to 203 (21 residues), see Phobius details PF03006: HlyIII" amino acids 5 to 196 (192 residues), 150.2 bits, see alignment E=3.8e-48 TIGR01065: channel protein, hemolysin III family" amino acids 5 to 203 (199 residues), 208.4 bits, see alignment E=4.1e-66

Best Hits

Swiss-Prot: 39% identical to YQFA_ECOLI: UPF0073 inner membrane protein YqfA (yqfA) from Escherichia coli (strain K12)

KEGG orthology group: K11068, hemolysin III (inferred from 100% identity to psb:Psyr_0452)

Predicted SEED Role

"COG1272: Predicted membrane protein hemolysin III homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZZA0 at UniProt or InterPro

Protein Sequence (204 amino acids)

>Psyr_0452 HylII (Pseudomonas syringae pv. syringae B728a)
MYYGEKFNAWSHLVGAVLAAVGAIWLLVMASLHGDVWKVVSMAIYGVCLVTLYSVSTVYH
SVKGRSKSIMQKVDHFSIYLMIAGSYTPFCLVTLRGAWGWTLFGIVWGLALIGILQEIKP
RSEARIMSIVIYAVMGWIVLVAVKPLLAALGVSGFIWLAGGGVLYTVGILFFAYDQIRHF
HGIWHLFVIAGSLMHFVAICFYVL