Protein Info for Psyr_0364 in Pseudomonas syringae pv. syringae B728a

Annotation: sodium/proton antiporter, NhaA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 56 to 78 (23 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details amino acids 127 to 147 (21 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 212 to 240 (29 residues), see Phobius details amino acids 262 to 286 (25 residues), see Phobius details amino acids 296 to 321 (26 residues), see Phobius details amino acids 332 to 355 (24 residues), see Phobius details amino acids 367 to 386 (20 residues), see Phobius details PF06965: Na_H_antiport_1" amino acids 18 to 384 (367 residues), 478.4 bits, see alignment E=7.5e-148 TIGR00773: Na+/H+ antiporter NhaA" amino acids 19 to 384 (366 residues), 441 bits, see alignment E=1.8e-136

Best Hits

Swiss-Prot: 100% identical to NHAA1_PSEU2: Na(+)/H(+) antiporter NhaA 1 (nhaA1) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K03313, Na+:H+ antiporter, NhaA family (inferred from 100% identity to psb:Psyr_0364)

MetaCyc: 54% identical to Na+:H+ antiporter NhaA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-129; TRANS-RXN-292

Predicted SEED Role

"Na+/H+ antiporter NhaA type" in subsystem Na(+) H(+) antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZZI6 at UniProt or InterPro

Protein Sequence (391 amino acids)

>Psyr_0364 sodium/proton antiporter, NhaA family (Pseudomonas syringae pv. syringae B728a)
MTQVPNRETPRGIAILARFLASESAGGIVLMVAALAALIVANSPLSAGYFSILHSVWLGL
SVELWINDGLMAIFFLMVGLEIKREVLAGGLASWGQRALPGFAAAGGMLVPALIYIAINW
GNPQTLSGWAIPAATDIAFALGVLSLLGNRVPTSLKVFLAALAILDDLGAVTIIAFFYSA
GLNLPMLAAAFVTLAVLIVMNRLNVRRLLPYLLLGALLWFFVLQSGVHATLAGVALALCI
PMGKPEEEARSPLLFLEEKMHYWVAFAVVPIFGFANAGVSLAGITLGNLVDPVPLGVALG
LFVGKQIGVFLAAVLAIRAGLAVLPEGSNWVQLYGVAMLCGIGFTMSLFIGNLAFPGSQH
LIDEVKVGVLIGSGLAAIAGIVLLRSRFSRP