Protein Info for Psyr_0313 in Pseudomonas syringae pv. syringae B728a

Annotation: Zinc-containing alcohol dehydrogenase superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details PF08240: ADH_N" amino acids 28 to 87 (60 residues), 43.1 bits, see alignment E=5.1e-15 PF00107: ADH_zinc_N" amino acids 151 to 270 (120 residues), 112.5 bits, see alignment E=2e-36 PF13602: ADH_zinc_N_2" amino acids 184 to 322 (139 residues), 84.6 bits, see alignment E=1.9e-27

Best Hits

Swiss-Prot: 40% identical to QORL2_RAT: Quinone oxidoreductase-like protein 2 from Rattus norvegicus

KEGG orthology group: K00344, NADPH2:quinone reductase [EC: 1.6.5.5] (inferred from 100% identity to psb:Psyr_0313)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZZN7 at UniProt or InterPro

Protein Sequence (328 amino acids)

>Psyr_0313 Zinc-containing alcohol dehydrogenase superfamily (Pseudomonas syringae pv. syringae B728a)
MKALLCKAFGPASTLVLEDVPGPAIKKNEILLDVHAAGVNFPDTLIIEGKYQFKPPFPFS
PGGEAAGVIAAVGENVSHLKPGDRVMALTGWGSFAEQVAVPHYNVLPIPQGMDFTTAAAF
SMTYGTSMHALTQRARLQPGEILLVLGASGGVGLAAVEIGKALGARVIAAASSAEKLEVA
RNAGADELINYSETSLKDEIKRLTHGNGADVIYDPVGGDLFDQAIRSIAWNGRLLVVGFA
SGRIPELPVNLTLLKGASVVGVFWGSFAQRQPQDNAANFKQLFAWFEEGKLKPLVSTVYP
LERAGEAIDLLGGRRAVGKVVVLIGKTA