Protein Info for Pf6N2E2_860 in Pseudomonas fluorescens FW300-N2E2
Annotation: Altronate dehydratase (EC 4.2.1.7)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01685, altronate hydrolase [EC: 4.2.1.7] (inferred from 78% identity to ppu:PP_2834)MetaCyc: 70% identical to D-arabinonate dehydratase (Herbaspirillum huttiense)
Arabinonate dehydratase. [EC: 4.2.1.5]
Predicted SEED Role
"Altronate dehydratase (EC 4.2.1.7)" (EC 4.2.1.7)
MetaCyc Pathways
- D-arabinose degradation IV (4/6 steps found)
- D-galacturonate degradation I (3/5 steps found)
- D-arabinose degradation III (3/6 steps found)
- superpathway of hexuronide and hexuronate degradation (5/10 steps found)
- superpathway of microbial D-galacturonate and D-glucuronate degradation (16/31 steps found)
- superpathway of pentose and pentitol degradation (15/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.2.1.5 or 4.2.1.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A165YX30 at UniProt or InterPro
Protein Sequence (515 amino acids)
>Pf6N2E2_860 Altronate dehydratase (EC 4.2.1.7) (Pseudomonas fluorescens FW300-N2E2) MELIMKTGAAAVLRLNPLDDVLIARRPLLAGEILEQEGVTIRQAIVPGHKVASRRIEAGQ PVRRYGQIIGFAVVDIEAGEHIHVHNLAMGEFARDYAFSVDAKPSVTPSEAPSFMGIVRP DGRVATRNYIGILTSVNCSATVARAIADHFRRDINPAALQAYPNVDGVVALTHSAGCAVD PAGDGLSMLRRTLAGYATHANFAAVLVIGLGCETNQIDSLLTTQGLTRSNTLRTFNIQDS GGTSKAIASGIDHVKQLLGEANQIQREPVSARHLTVGLQCGGSDGYSGITANPALGNAVD RLVACGGTAILSETPEIYGAEHLLTRRAVSREVGEKLIARIHWWEQYCERMGAELNNNPS AGNKAGGLTTILEKSLGAVAKAGSSNLMDVYEYAQAVTANGLVFMDTPGYDPVSATGQVA GGANLIAFTTGRGSAYGCAPAPSIKLATNSALWARQREDMDINCGEIAEDTLTIEACGAA IFETMLRIASGERSMSEQHGYGQNEFVPWQIGAVT