Protein Info for Pf6N2E2_815 in Pseudomonas fluorescens FW300-N2E2

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1160 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details amino acids 261 to 278 (18 residues), see Phobius details PF05227: CHASE3" amino acids 46 to 178 (133 residues), 131.3 bits, see alignment E=7.2e-42 PF13185: GAF_2" amino acids 252 to 388 (137 residues), 59.5 bits, see alignment E=1.3e-19 PF01590: GAF" amino acids 255 to 387 (133 residues), 43.8 bits, see alignment E=1.2e-14 PF00512: HisKA" amino acids 487 to 554 (68 residues), 65.2 bits, see alignment 1.4e-21 PF02518: HATPase_c" amino acids 602 to 711 (110 residues), 100 bits, see alignment E=3.3e-32 PF00072: Response_reg" amino acids 770 to 876 (107 residues), 59 bits, see alignment E=1.4e-19 amino acids 892 to 1001 (110 residues), 55.1 bits, see alignment E=2.5e-18 amino acids 1038 to 1150 (113 residues), 89.9 bits, see alignment E=3.8e-29

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a3082)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZU95 at UniProt or InterPro

Protein Sequence (1160 amino acids)

>Pf6N2E2_815 Signal transduction histidine kinase (Pseudomonas fluorescens FW300-N2E2)
MTPSSSVDEQSFRKLLSRNISLPLGMGALSSVFFIILVTYLLSVIQWVGHTDRVINNANE
ALKLSVDLETGMRGYLLNGDEHFLEPYEVAKPRIAVALDTLLELTADNPVQTDRLHKIQA
IQTEWSTYAQGLIDLQRSSGDYRSAARSGRGKRLTDEIRQTFEEIVDTEQQLRAARNQDV
RTTTVWSIGLYLLFVAAVSGLLAYVGRRDLLSLSESYSASLKVQQRSALHLEKQAWLRNG
QTQLAEQVLGQLSLDLLGRNILQFCAKYLGVAVAALYVREENGVLKRVASYGLSREDDAQ
QQVIVDGEGIAGQAVRQGRLIRLDDVPDDYLKVSSGLGQGLPNSVLVAPTSDDDRINGVI
ELGFLRPLTERDIEMLELISGNIGTSIEAARYRQRLQEVLAETQQLNEELQVQQEELKTA
NEELEEQSRILKESQAHLEAQQQELEQTNEQLAEQRDAMDQKNSELNLAQIQLQERAEEL
QRSSKYKSEFLANMSHELRTPLNSSLILSKLLSENPQQNLSEEQVKFAESIYSAGNDLLN
LINDILDISKVEAGKLEVRPENTSVQRLVEGLRDMFEPLAVDKGLEFEVQVLPDAPAMLY
TDRQRLEQVIKNLLSNAVKFTEQGTVSLSVAGQPGSGIAFMVRDSGIGIAADQQQSIFEA
FRQADGTTNRRYGGTGLGLSISRDLATLLGGSISVSSEPGQGSVFTLVMPERYVEPGESP
IEPLTFIPTATAPAPAAPKAAPAPLIAEVDTPIARFADDRDKAPFDTRCILVIEDEPKFA
RILFDLAHELGYQCLVAHGADEGFDLALQLAPDAILLDMRLPDHSGLTVLQRLKERAETR
HIPVHVISVEDRVEAAMHMGAIGYAVKPTTREELKDVFARLEAKLTQKVKRVLLVEDDDL
QRDSITRLIGDDDIEITAVGLAQQALDLLRTNVYDCMIIDLKLPDMLGNDLLKRMSSEDI
CSFPPVIVYTGRNLTRDEEAELRKYSRSIIIKGARSPERLLDEVTLFLHKVESRLSHERQ
RMLKTARSRDKVFEGRKVLLVDDDVRNIFALTSALEAKGAIVVIGRNGLEAIDRLNEFDD
IDLVLMDVMMPEMDGFEATALIRKDPRWRKLPIIAVTAKAMKDDQERCLAAGSNDYLAKP
IDLDRLFSLIRVWLPNMERI