Protein Info for Pf6N2E2_621 in Pseudomonas fluorescens FW300-N2E2

Annotation: TPR domain protein in aerotolerance operon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 310 to 336 (27 residues), see Phobius details PF13519: VWA_2" amino acids 96 to 199 (104 residues), 37.1 bits, see alignment E=8.3e-13 PF07719: TPR_2" amino acids 403 to 435 (33 residues), 33.5 bits, see alignment (E = 5.2e-12) PF00515: TPR_1" amino acids 403 to 435 (33 residues), 38.9 bits, see alignment (E = 1e-13) PF13181: TPR_8" amino acids 403 to 435 (33 residues), 25.6 bits, see alignment (E = 1.8e-09)

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 96% identity to pba:PSEBR_a3256)

Predicted SEED Role

"TPR domain protein in aerotolerance operon"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165YVF2 at UniProt or InterPro

Protein Sequence (578 amino acids)

>Pf6N2E2_621 TPR domain protein in aerotolerance operon (Pseudomonas fluorescens FW300-N2E2)
MIAFWPHWLRPWFVLLLPLLGWLLWQLWHRQKRVGRWQMILPPAFHTVLLSGGSGRESRL
PWIALGLGWLLIVLALLGPSWARVEQTSQKPADPLVVVLELTPEMLATDVPPTRLEQARR
KVLDLLQNRSDAQTAIIVYAGSAHTLVPLSDDLSTSANLLEALAPSIMPQSGHRADLAVR
KALALLDQGELGHGRILLIGSSLNEQERQGIRQALDGSATQWLMLGIGTREGAPVPQEDG
SYLKDAQGSILLPRLDSPGLKAFANKLDGRYRPARLDDSDLRGLGLLDGPRHLRSDGQTL
RLDTWADQGYWLLLPLLLLAACAGRRGWLFCLPLLFMLPQTGHAFEFQDLWLRADQQGQH
LLKQKRPAEAAAHFEDSQWQGVALYEAGQYSEAARRFAEGNDARAHYNRGNALARSGELE
AALDAYEQALELQPDLRPAQTNKALVESLLKQPAPVPEEPKPAESEEPARAEQSPDTDSP
TQSSEPGQPSVETSATSDEPQPPRTAQPPTAQDVPGSELPDEQTTTPPLRPAAGQRNEEE
QRQALEQWLRQIPDNPGELLRRKFWYEQQSHQAQEKTK