Protein Info for Pf6N2E2_5705 in Pseudomonas fluorescens FW300-N2E2

Annotation: Sensor protein PhoQ (EC 2.7.13.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 166 to 188 (23 residues), see Phobius details PF02518: HATPase_c" amino acids 347 to 447 (101 residues), 65.1 bits, see alignment E=3.8e-22

Best Hits

KEGG orthology group: K07637, two-component system, OmpR family, sensor histidine kinase PhoQ [EC: 2.7.13.3] (inferred from 99% identity to pba:PSEBR_a4276)

Predicted SEED Role

"Sensor protein PhoQ (EC 2.7.13.3)" in subsystem Lipid A modifications (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A5Y1 at UniProt or InterPro

Protein Sequence (448 amino acids)

>Pf6N2E2_5705 Sensor protein PhoQ (EC 2.7.13.3) (Pseudomonas fluorescens FW300-N2E2)
VIRSLRLRLMLAAMTLAVLFMLALLPAMQGAFSLALQESIEQRLASDVTTLISAARVENN
RLRMPAQLPDERFNLADARLLGYIYDREGRLVWRSKATQEENINYTPRYDGQGNQFARIR
ENDGQEFFVYDVEIKLLGGQSAAFSIVTLQPVRDYEVTLQGLRDNLYLGFGAALLVLLAL
LWIGLTWGLRALRRLSQELDEIESGARESLSTEHPRELLRLTGSLNRLLYSEREQRSRYR
DSLDDLAHSLKTPLAVLQGVSEDMARRPEDRGQAWVLQTQIERMSQQIGYQLQRASLRKS
GLVRHQVRLRPVLQSLCDTLDKVYRDKRVNVSFDLPEHCQVPIEQGALLEMLGNLLENAY
RLCLGEVRVSVHQTLGGTELSVEDDGPGVPPDQRARILQRGERLDRQHPGQGIGLAVVED
IIESYGAKLTLGDSELGGAAFRIHFPVV