Protein Info for Pf6N2E2_5664 in Pseudomonas fluorescens FW300-N2E2

Annotation: Arginine pathway regulatory protein ArgR, repressor of arg regulon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00165: HTH_AraC" amino acids 217 to 256 (40 residues), 32.8 bits, see alignment 6e-12 amino acids 271 to 305 (35 residues), 26.9 bits, see alignment 4.1e-10 PF12833: HTH_18" amino acids 230 to 308 (79 residues), 83.9 bits, see alignment E=8e-28

Best Hits

Swiss-Prot: 80% identical to ARGR_PSEAE: HTH-type transcriptional regulator ArgR (argR) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 99% identity to pba:PSEBR_a4320)

Predicted SEED Role

"Arginine pathway regulatory protein ArgR, repressor of arg regulon" in subsystem Arginine Biosynthesis extended or Arginine Deiminase Pathway or Arginine and Ornithine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161H417 at UniProt or InterPro

Protein Sequence (326 amino acids)

>Pf6N2E2_5664 Arginine pathway regulatory protein ArgR, repressor of arg regulon (Pseudomonas fluorescens FW300-N2E2)
MTAHRIGFLIWPSTKALTLALAEEALRVAQRVHPDVVYELSFLQAEPPIDGAWQLPGEPW
AGKLEGLQKLFLLADEPPAALASSLSSALKQLVRAGCVIGGLSAGVYPLAQLGLLDGYRA
AVHWRWQDDFSERFPKVIATSHLFDWDRDRLSACGGMSVLDLLLAVLARDHGAELAGAVS
EELVVERIREGGERQRIPLQNRLGSSHPKLTQAVLLMEANIEEPLTTDEIAQHVCVSRRQ
LERIFKQYLNRVPSQYYLELRLNKARQMLMQTSKSIIQIGLSCGFSSGPHFSSAYRNFFG
ATPREDRNQRRSSSPFELSSVPSERG