Protein Info for Pf6N2E2_5609 in Pseudomonas fluorescens FW300-N2E2

Annotation: DNA-binding response regulator ColR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 PF00072: Response_reg" amino acids 3 to 114 (112 residues), 106.7 bits, see alignment E=7.5e-35 PF00486: Trans_reg_C" amino acids 148 to 220 (73 residues), 63.4 bits, see alignment E=1.7e-21

Best Hits

Swiss-Prot: 40% identical to CZCR_CUPMC: Transcriptional activator protein CzcR (czcR) from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)

KEGG orthology group: None (inferred from 96% identity to pen:PSEEN4458)

Predicted SEED Role

"DNA-binding response regulator ColR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WTY0 at UniProt or InterPro

Protein Sequence (227 amino acids)

>Pf6N2E2_5609 DNA-binding response regulator ColR (Pseudomonas fluorescens FW300-N2E2)
MRILLVEDNRDILANLADYLGLKGYTVDCAQDGLSGLHLAATEHYDLIVLDIMLPGIDGY
TLCKRLREDARRDTPVIMLTARDQLDDRLQGFKSGADDYLIKPFALSELAARIEAVMRRA
QGGGRRALQVGDLSYDLDTLEVTREGKLLKLNPVGLKLLAVLMQKSPHVLRREILEEALW
GDDCPDSDSLRSHVHQLRQVIDKPFDKPLLHTVHGVGYRLAEGRDGV