Protein Info for Pf6N2E2_5518 in Pseudomonas fluorescens FW300-N2E2

Annotation: Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-) / Thiamin-phosphate pyrophosphorylase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 TIGR00586: mutator mutT protein" amino acids 1 to 120 (120 residues), 109.5 bits, see alignment E=6e-36 PF00293: NUDIX" amino acids 2 to 116 (115 residues), 63.3 bits, see alignment E=3.7e-21 PF14815: NUDIX_4" amino acids 3 to 119 (117 residues), 90.6 bits, see alignment E=9.1e-30 PF02581: TMP-TENI" amino acids 127 to 304 (178 residues), 126.1 bits, see alignment E=1.6e-40

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a4456)

Predicted SEED Role

"Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-) / Thiamin-phosphate pyrophosphorylase-like protein" in subsystem Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-

Use Curated BLAST to search for 3.6.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GTY4 at UniProt or InterPro

Protein Sequence (309 amino acids)

>Pf6N2E2_5518 Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-) / Thiamin-phosphate pyrophosphorylase-like protein (Pseudomonas fluorescens FW300-N2E2)
VAAAVIRDAAGKILIARRADTQHQGGLWEFPGGKVEADESVETALARELHEELCIVVDAA
RPLIKVRHDYPDKQVLLDVWEVSAFTGQPHGAEGQPLAWVTARDLTNYEFPAANQPIVAA
ARLPGEYLITPDGLETPALLRGMQKAIAGGIKLVQLRAPNGYDPQYRDLAVDAAGLCAGK
AQLMLKGPFEWLGDFPSAGWHITAAQLRKHAAAGRPFGKDRWLAASCHNAEELSLAQQMD
VDFVTLSPVQPTQTHPDVQPLGWAEAARLIEGFNRPVYLLGGVGPGERQKAWEAGAQGVA
GIRAFWPEA