Protein Info for Pf6N2E2_5461 in Pseudomonas fluorescens FW300-N2E2

Annotation: Ferredoxin-dependent glutamate synthase (EC 1.4.7.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 31 to 50 (20 residues), see Phobius details PF01645: Glu_synthase" amino acids 157 to 474 (318 residues), 270.8 bits, see alignment E=1e-84

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a4517)

Predicted SEED Role

"Ferredoxin-dependent glutamate synthase (EC 1.4.7.1)" in subsystem Ammonia assimilation or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.7.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.7.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A3W2 at UniProt or InterPro

Protein Sequence (539 amino acids)

>Pf6N2E2_5461 Ferredoxin-dependent glutamate synthase (EC 1.4.7.1) (Pseudomonas fluorescens FW300-N2E2)
MSLSLLSRYAFFAGCVIFTLVSLPFLQHDWLWPMALVTGLLSLLGLFDLLQSRHAVRRNY
PILGNIRYLVEGIRPEIRQYLLESDSEALPFSRAQRSLVYSRAKNESADKPFGTLIDVYQ
TGFEFIGHSMRPAPLSDPSGFRVTVGGPQCTQPYSASVFNISAMSFGSLSANAIRALNQG
AKLGNFAHDTGEGSISPYHREHGGDLTWELGSGYFGCRTSDGRFDPERFAAQAQNPQVRM
IEIKMSQGAKPGHGGILPKHKVTREIAETRGILMGEDCVSPSRHSAFSTPIELMQFVQQL
RELSGGKPVGFKFCLGHPWEFMGIAKAMLETGILPDFIVVDGKEGGTGAAPVEFTDHIGV
PLREGLLFVHNTLVGLNLRDKIKLGASGKIVSAFDIASVLAIGADWANAARGFMFAIGCI
QSQSCHTNKCPTGVATQDTLRQRALVVPDKAQRVYNFHRNTLKALAEMLAAAGLEHPSQL
QPKHLVRRMSATEIKLFSQLHVFLKPGELLTGEVNGAFYSRMWQMARADSFEPEKIVAA