Protein Info for Pf6N2E2_5282 in Pseudomonas fluorescens FW300-N2E2

Annotation: Oxidoreductase, short chain dehydrogenase/reductase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 PF00106: adh_short" amino acids 10 to 196 (187 residues), 141.2 bits, see alignment E=6.1e-45 PF08659: KR" amino acids 12 to 175 (164 residues), 65.6 bits, see alignment E=1.1e-21 PF01370: Epimerase" amino acids 12 to 161 (150 residues), 23.8 bits, see alignment E=5.7e-09 PF13561: adh_short_C2" amino acids 16 to 196 (181 residues), 112.2 bits, see alignment E=6e-36

Best Hits

Swiss-Prot: 56% identical to Y0148_MYCTU: Putative short-chain type dehydrogenase/reductase Rv0148 (Rv0148) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a4703)

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165ZNW9 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Pf6N2E2_5282 Oxidoreductase, short chain dehydrogenase/reductase family (Pseudomonas fluorescens FW300-N2E2)
MSESVRFEDKVVIVTGAGGGLGRAHALLFAKQGAKVLVNDLGGSAQGEGANASAADRVVA
EIREAGGIAEANHDSVTDGDKLVQNALDAFGRVDVVVNNAGILRDKTFHKMDDADWDLVY
RVHVEGAYKVTRAAWPHLREQNYGRVIFTASTSGIYGNFGQSNYGMAKLGLYGLTRTLAI
EGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQLKPELVSPLVVYLASETCQETSGLFEVG
GGWMGKVRWERSLGAGFDPRKGFSPEDVAAHWQQICDFEGAVHPNDNLEALKEMMANLQR
YAV