Protein Info for Pf6N2E2_519 in Pseudomonas fluorescens FW300-N2E2

Annotation: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01408: GFO_IDH_MocA
  • amino acids 1 to 118 (118 residues), 72.1 bits, E=6.6e-24
• PF02894: GFO_IDH_MocA_C
  • amino acids 132 to 339 (208 residues), 70.1 bits, E=2.6e-23

Best Hits

KEGG orthology group: None (inferred from 95% identity to pba:PSEBR_a3349)

Predicted SEED Role

"Myo-inositol 2-dehydrogenase (EC 1.1.1.18)" in subsystem Inositol catabolism (EC 1.1.1.18)

MetaCyc Pathways

• myo-inositol degradation I (7/7 steps found)
• myo-, chiro- and scyllo-inositol degradation (7/10 steps found)
• myo-inositol degradation II (1/5 steps found)
• streptomycin biosynthesis (3/18 steps found)

KEGG Metabolic Maps

• Inositol phosphate metabolism
• Streptomycin biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.18

Use Curated BLAST to search for 1.1.1.18

Sequence Analysis Tools

See A0A159ZT65 at UniProt or InterPro

Protein Sequence (350 amino acids)

>Pf6N2E2_519 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) (Pseudomonas fluorescens FW300-N2E2)
MRIGLVGYGKGGRFFHAPLISSLPGATFVGVVTRSVERREQLASDYPHVQAFDTLEQLVA
AGVDAVVVSTPLDGRPTVVMEAIERGVAVVSDKPFARDAAEAEAMVLAAERRNVPLCVYQ
NRRWDSDFLTLRKLLASGALGQVIRFESSVERYSPTSVGKGSGGGFLRDLGSHLVDQALQ
LFGPVVRVYAELDYRQPDQVFDNGFFMSLTHASGVISHLSGNCVQNAARPRFRVNGTQGC
YTVEGLDGQEAQALAGLSPASEGERWGAEEHRRWGWFEHGTERERVTSERGCWLAFYQHL
QTALQGAGPLPVEARDALATTRILDAARQSAEQGEVVRLSTPVGHGIKNE