Protein Info for Pf6N2E2_5085 in Pseudomonas fluorescens FW300-N2E2

Annotation: Lanthionine biosynthesis protein LanM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1027 transmembrane" amino acids 678 to 697 (20 residues), see Phobius details amino acids 718 to 740 (23 residues), see Phobius details TIGR03897: type 2 lantibiotic biosynthesis protein LanM" amino acids 106 to 1012 (907 residues), 547.8 bits, see alignment E=2e-168 PF13575: DUF4135" amino acids 186 to 556 (371 residues), 250.9 bits, see alignment E=2.4e-78 PF05147: LANC_like" amino acids 673 to 1018 (346 residues), 176.3 bits, see alignment E=6.9e-56

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A163 at UniProt or InterPro

Protein Sequence (1027 amino acids)

>Pf6N2E2_5085 Lanthionine biosynthesis protein LanM (Pseudomonas fluorescens FW300-N2E2)
MLVNALKLDQRGKYRYASDGDIALFENNLTRLHADDQTVLDHFGLNREQLVSYIKETVNQ
QPLPSAGEDALNTLKEKLIHLDSVNVDMKQGSSNKDNFYWFGYRFFLYFIDTFKADARYS
NASRHIDEPALFASLERYVLARVGRTSEQSLVHYLNTRIADGDDIDLEGFNHLLRTLPLL
KFFESYPVLATLLFDLLDDTLHFLYTVIHNFADDAEWLETAFSIPSRKIDAIELGLGDPH
GRGETVCQVNIGTTALVYKPRASQEALFFYGLLGQLHEWTGADCFSIHTPKILSRERHSW
VEKVENLPCDSETDIGLFYQKMGAQIAVIHGLNGIDFHYENIIACGNSPVMIDLECLFTA
STSDLLTDLPAGCALSNSFKLVQQSVCSSGFVPFSQQPNNDQSGLTRQALFISTRHSLIF
DDGFYHLRKVEFEHHLMQKHLPLLQGERKGPEAYKKELFQGFEKAYGELMVHRRAIMQML
EQSAGELSTRVLLKNSQRYADFIGLIRHPRFMQNMLDRELLLATLWEDLKEPYREKGIPR
YEIADLQRSSIPCFTMPLNGNYFTSAQGETIEMAAVEPPVKSCLQKIANLSRKDWALQRT
LLEICLFPEPNGHPPSPIPQTLANLETAPLANRLDALQTISARLEELAVVGMTEDVSWLS
FHTHPTTQRKYPSPMDHGLYSGIAGIGLFYLGLFKVSGEPHCLSRMDQVLHSLEQRFGFF
RTDLTVSAYHGLGAYLYLLINRRQVTGDAKHDEKIAGLLRQLIEVPPEDYDFDFLGGCCG
AVTLLANIHALSAQEDVLPAIQRMVGYIKDQVLIEDGQLLRRDDRSVILTGLSHGLSGVI
HALCKAYDVTGDATLVPLAIQVLEGENRLSRDGFWLDLRNLGPADHTSKWCHGDGGILIA
RRQLMASMGDALDDAARQTVLDDIQRCENNLWQHGFGEGYNLCHGDFGNLICLHDLYRHS
DNPEGMSRVRKILDEIARQFFEGPWLDNDRVPDVSLLTGITGAGYALLYEMDPTLPNILS
LEFAVPA