Protein Info for Pf6N2E2_503 in Pseudomonas fluorescens FW300-N2E2

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details amino acids 159 to 182 (24 residues), see Phobius details amino acids 421 to 438 (18 residues), see Phobius details PF00672: HAMP" amino acids 182 to 233 (52 residues), 48.5 bits, see alignment 8.7e-17 PF02518: HATPase_c" amino acids 350 to 454 (105 residues), 82.5 bits, see alignment E=3e-27

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a3363)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZU72 at UniProt or InterPro

Protein Sequence (461 amino acids)

>Pf6N2E2_503 sensor histidine kinase (Pseudomonas fluorescens FW300-N2E2)
MSLLNPAKGWRSSSSRLLALYSSLFVIWSAILMGVMYYEVFGYLDSLAKHSLMQRQHLFA
RIHGDQLEDALMASLTLDERGVDAYGLFDPQLRHLSGPIVRIPADLPLDGKIHMLGGCVD
SDDPSVPSDSCDAVASRTQDGRWLVLARDNGSLFAVTRIILHALFWGVSLTILPGIAGWH
LLRRRPLRRIRQLQASAEAIVAGDLTHRLPLSSRRDELDMLAAIVNAMLDRIERLMNEVK
GVCDNIAHDLRTPLTRLRAQLYRIQQQAPDGSPEALQMDQVIAETDTLMARFRGLLRISE
LEDQQRRSGFVRLDPLQLLQELHDFYLPLAEEGELTFSLEVPDALPLLNGDRALLFEAVS
NLLSNSIKFTPPGGTVILRGVDQGDSTRIEVLDSGPGIPEAERKAVFRRFYRAEGSSQHG
GFGLGLSIVAAIVNLHGFTLEVGSSEHGGARLVLDCRGTLL