Protein Info for Pf6N2E2_4762 in Pseudomonas fluorescens FW300-N2E2

Annotation: Biotin synthesis protein BioH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF12697: Abhydrolase_6" amino acids 6 to 231 (226 residues), 29.3 bits, see alignment E=1.4e-10 PF00561: Abhydrolase_1" amino acids 54 to 226 (173 residues), 32.7 bits, see alignment E=6.4e-12

Best Hits

KEGG orthology group: K02170, biotin biosynthesis protein BioH (inferred from 96% identity to pba:PSEBR_a5179)

Predicted SEED Role

"Biotin synthesis protein BioH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A0K0 at UniProt or InterPro

Protein Sequence (243 amino acids)

>Pf6N2E2_4762 Biotin synthesis protein BioH (Pseudomonas fluorescens FW300-N2E2)
MRDRLILLPGWGLGVSPLEPLAAALHGLDEHLRVEIEPLPALLSNDPDEWLEELDAIVPQ
DAWLGGWSLGGMLASALAARRGERCCGLLTLASNPSFVAHEQWPSAMDGATFDGFLAGCA
ADPRQTLKRFSLLCAQGSSDPRGLSRLLLAGAPGTSPEVLMAGLELLAQLDTRAALQRFR
GPQLHLFAGLDALVPAEAAGELLVLLPDVEIGLIEQAGHGFLLEDPHGVAGAIQAFLHES
GDD