Protein Info for Pf6N2E2_4575 in Pseudomonas fluorescens FW300-N2E2

Annotation: Coniferyl aldehyde dehydrogenase (EC 1.2.1.68)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 transmembrane" amino acids 131 to 147 (17 residues), see Phobius details PF00171: Aldedh" amino acids 23 to 445 (423 residues), 290.3 bits, see alignment E=1.2e-90

Best Hits

Swiss-Prot: 76% identical to CALB_PSEAE: Probable coniferyl aldehyde dehydrogenase (calB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00154, coniferyl-aldehyde dehydrogenase [EC: 1.2.1.68] (inferred from 98% identity to pba:PSEBR_a5345)

Predicted SEED Role

"Coniferyl aldehyde dehydrogenase (EC 1.2.1.68)" (EC 1.2.1.68)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.1.68

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A068 at UniProt or InterPro

Protein Sequence (476 amino acids)

>Pf6N2E2_4575 Coniferyl aldehyde dehydrogenase (EC 1.2.1.68) (Pseudomonas fluorescens FW300-N2E2)
MPADVAYLHESQQQLDELRSLFVAQRQAYAAHPMPPAEQRRQWLKALREVLSNERQAVID
AISQDFSHRSADETLLAELMPSLHGIHYASRHLQGWMKPSRRKVGMAFQPASAKVIYQPL
GVVGVIVPWNYPLFLAIGPLVGALAAGNRVMLKLSESTPATGLLLKQLLARVFPQDLVCV
VLGEAEIGMAFSKLPFDHLLFTGATSIGKHVMRAAAENLTPVTLELGGKSPAIVSVDVPI
KDAAERIAFGKTLNAGQTCVAPDYVLVPQNCVGEFVEAYREAVRGFYPTLANNPDYTAII
NERQLARLNGYISDATSKGALLIELFDQGQDRRMAHSLLLNVSDEMTVMQDEIFGPLLPI
VPYDNLDQALAYINQRPRPLALYYFGYNKAEQNRVLHETHSGGVCLNDTLLHVAQDDLPF
GGIGPSGMGHYHGHEGFLTFSKAKGVLTKQRFNAAKLIYPPYGKPLQKLIQKLFVR