Protein Info for Pf6N2E2_4459 in Pseudomonas fluorescens FW300-N2E2

Annotation: Transcriptional regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF00392: GntR" amino acids 13 to 71 (59 residues), 61 bits, see alignment E=7e-21 PF07729: FCD" amino acids 96 to 219 (124 residues), 91.4 bits, see alignment E=6.3e-30

Best Hits

KEGG orthology group: K05799, GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex (inferred from 97% identity to pba:PSEBR_a5450)

Predicted SEED Role

"Transcriptional regulator, GntR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A1H0 at UniProt or InterPro

Protein Sequence (235 amino acids)

>Pf6N2E2_4459 Transcriptional regulator, GntR family (Pseudomonas fluorescens FW300-N2E2)
MNSIARAVPEVALQAIRKLITDEGFGPGDALPSQRDLALQLGVSRASLREALSSLSALGM
ISVQPGKGVFVQAPLEAPRSESAPGWPFAAQASPVDIFQLRYALEGFAAGLAAVTLSADE
LDMLQDNVEAMRRELKIGDFDAAARLDFEFHRRILLASGNQAMLSILTASAEIFLESQKL
PFIRAERAMETWQEHRKILRALARRASGAAQKAMQEHVRNAALRTGIAFVAPVAS