Protein Info for Pf6N2E2_4405 in Pseudomonas fluorescens FW300-N2E2

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 90 to 114 (25 residues), see Phobius details PF02518: HATPase_c" amino acids 303 to 413 (111 residues), 66.8 bits, see alignment E=1.1e-22

Best Hits

KEGG orthology group: None (inferred from 97% identity to pba:PSEBR_a5494)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GTP8 at UniProt or InterPro

Protein Sequence (425 amino acids)

>Pf6N2E2_4405 sensor histidine kinase (Pseudomonas fluorescens FW300-N2E2)
MNDLLALLTDKRFMPHGHCYMWRPDLLWTNVIADSLIALSYVTIPFTLLYFIHKRKDVPF
DWMLAAFGVFILACGTSHVMEILTIWQPYYWLMALVKVITAIASVITAILLVRLVPAALK
IPSPQQLAKVNDELREAQAELVTTARRAGMAEIATNVLHNVGNVLNSVNVSAQVLYEKVH
TSKGPGVAKVVQLMKEHPDDLGDFISSDPKGRALPDYLDKLADALAVEQQGMIAELAQLT
RRIDHIKEIVATQQSYAGNASVLEPGSLRELVEDVVRICDVSLARHHITLIKEFSDIPQM
PLDKHRVLQILVNLINNAKQALDAGVNRPPQIILRLKVVDDGRVRVEVQDNGEGIAQDNL
ARVFEHGFTTRVDGHGFGLHSCILAAHEMGGDLTAQSAGPGQGALFILELPLALTPAPSQ
RVAGG