Protein Info for Pf6N2E2_4401 in Pseudomonas fluorescens FW300-N2E2

Annotation: Glycine cleavage system transcriptional activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF00126: HTH_1" amino acids 10 to 67 (58 residues), 77.1 bits, see alignment E=8.3e-26 PF03466: LysR_substrate" amino acids 89 to 293 (205 residues), 105.4 bits, see alignment E=2.7e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to pba:PSEBR_a5498)

Predicted SEED Role

"Glycine cleavage system transcriptional activator" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GLD9 at UniProt or InterPro

Protein Sequence (306 amino acids)

>Pf6N2E2_4401 Glycine cleavage system transcriptional activator (Pseudomonas fluorescens FW300-N2E2)
MSRRLPPLYALRAFEAAARYSSFTRAAEELSITQSAVSRHIRTLEDHFACRLFLRSGRNL
QLTEAARLLLPGVREGFMALERACHTLHGEDGILRMKAPSTLTMRWLLARLSRFRHLQPG
NEVQLTSAWMDVDSVDFNVEPFDCAVLLGNGHFPADWEASLLFPEELIPVGAPNLLNDQP
WDVARLASAELLHPTPDRRDWRNWLQRMGLSDKVSLKGGQVFDTLELGMIAAARGYGVSM
GDLLMVAEDVAQGRLSLPWPTAVASGEHYYLVWPKTRPGGERLRRLSDFLQGEVKAMQLP
DVQRLG