Protein Info for Pf6N2E2_4341 in Pseudomonas fluorescens FW300-N2E2

Annotation: IcmF-related protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1166 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 41 to 58 (18 residues), see Phobius details amino acids 441 to 462 (22 residues), see Phobius details TIGR03348: type VI secretion protein IcmF" amino acids 15 to 1164 (1150 residues), 1355.8 bits, see alignment E=0 PF14331: IcmF-related_N" amino acids 191 to 447 (257 residues), 322.1 bits, see alignment E=5.1e-100 PF06761: IcmF-related" amino acids 499 to 793 (295 residues), 304.2 bits, see alignment E=2.5e-94 PF21070: IcmF_helical" amino acids 934 to 1033 (100 residues), 38.5 bits, see alignment E=2.3e-13 PF06744: IcmF_C" amino acids 1041 to 1147 (107 residues), 111.6 bits, see alignment E=4.2e-36

Best Hits

KEGG orthology group: K11891, type VI secretion system protein ImpL (inferred from 99% identity to pba:PSEBR_a5552)

Predicted SEED Role

"IcmF-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZZQ6 at UniProt or InterPro

Protein Sequence (1166 amino acids)

>Pf6N2E2_4341 IcmF-related protein (Pseudomonas fluorescens FW300-N2E2)
VKAFFSFMTRWVIPLLGLIALSLIIWFVGPLLDWLVPEGRRWALIILVFAVWIAYRVFRI
IQARRQAAEVMRSLAAQTPPDPTSIATAEELETLRQRMDEALALLKKAKLGGDERRNLYE
LPWYVIIGPPGSGKTTALVNSGLHFPLAAQLGAGAVRGVGGTRNCDWWFTDQAVLLDTAG
RYTTQDSDATIDKAAWLGFLGLLKKQRARRPIDGAFIAISLSDLLLGSDAERAAHAAAIR
LRIQELYTQLGVRFPIYLMLTKLDLVPGFMEYFDTLSKEERAQVWGMTFALDDGKSSDSP
LAHLQSEFTGLEQRLNDRLVERLQQERDPARRDLIYGFPQQFGALKDCLQSFLEGVFKPN
AFEERVLLRGVYFTSGTQEGSPIDRLIGSMAQSMNLDRQHLARQTGTGRSYFIEKLFTAV
AFAERGLVGVDPKVERRRKWIARGVLASTVVLVLVVSTLWWVSYRANQAYIAQVDQKVAP
LGQTVQNLSPAQRDVLAVLPLLNAVKHLADDAPSWAEGLGLYQGDMLEAESGSVYRKLLI
AVFAPRLLTRIEEQLHSGGNSDFLYEGLKAYLMLADTEHYDADFIKAWIALDWDRSLPRD
LPAEQRQALTAHLQALFERRPPLARLDQRLVEDLRRQLQQLPVAQRVYDRIKRQKLPDGI
PDFRINEAAGRDAALVFSRKSGKPLGEPLSGFFTVKGYRQGFLLTSLSQTGTLAEEQWVL
GFEQADQQNVASLAADVRRLYFQDYLRQWDALLADIDFVPITSVAQAADVLRVISGPTSP
LKKLLVAVAKETDLQQDERLLAAQGAPVEGGVDKLKERLGSLLGQEQSTQNAPAQSDDPI
TAHFAELNSIVSKSEGEPAAIDGLLADMNALYVQVSAMVGASGDALLGEAKNQATAAATR
VSLNAERQPPLVQGLVKSVVNSTTNSMMGGVRNQLNAAWTSEVVNIYRQSLAGRYPMSPG
SARDATLDDFGQFFGVGGVMDNYFRKYLQPYVDTSTPTWRWQPGAAQKLGIAPGVLQTFQ
RAATIRDAFFRSGGTQPMVRFELKPVAMDSTITQFLLDLDGQQLSYDHGPSRPTAMQWPN
PGSIGVVRISIMPPSSSGRSGITLDGPWAWFRLLEQSDLTAGNSPDRFNLRLRVDGASAS
YELRANSAFNPFKSRVLSGFSLPERL