Protein Info for Pf6N2E2_4263 in Pseudomonas fluorescens FW300-N2E2

Annotation: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02492: cobW" amino acids 6 to 210 (205 residues), 190.9 bits, see alignment E=1.7e-60 PF07683: CobW_C" amino acids 256 to 373 (118 residues), 84.2 bits, see alignment E=4.9e-28

Best Hits

Swiss-Prot: 56% identical to P47K_PSECL: 47 kDa protein from Pseudomonas chlororaphis

KEGG orthology group: None (inferred from 97% identity to pba:PSEBR_a5607)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GT03 at UniProt or InterPro

Protein Sequence (402 amino acids)

>Pf6N2E2_4263 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family (Pseudomonas fluorescens FW300-N2E2)
MPNRLPVTVLSGFLGAGKSTLLNHVLRNRDNLRVAVIVNDMSEINIDGSEVQRDVTLSRS
EEKLVEMSNGCICCTLREDLLKEVGQLAREGRFDYLLIESTGISEPLPVAETFTFRDEEG
RSLADVARLDTLVTVVDGVNFLLDYQAAESLASRGETLGEEDERSITDLLIEQIEFADVI
LISKIDLISQHEREELTAILQRLNAQAQIIPMVMGQVPLGRILDTGLFDFERAAQAPGWL
QELRGEHVPETEEYGIASTAYRARRPFHPERFFNFIDRPWPNGKLLRSKGFFWLASKPEE
AGNWSQAGGLMRHGFAGRWWRFVPKNQWPQDEESTAAIMKNWLAATGDCRQELVFIGQDI
DFGQLAAELDACLLTDAEMALGVENWRLLPDPFGPWHDEVAA