Protein Info for Pf6N2E2_4112 in Pseudomonas fluorescens FW300-N2E2

Annotation: NADPH:quinone oxidoreductase 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF05368: NmrA" amino acids 2 to 220 (219 residues), 77.9 bits, see alignment E=1.6e-25 PF07993: NAD_binding_4" amino acids 4 to 42 (39 residues), 21 bits, see alignment 3.4e-08 PF13460: NAD_binding_10" amino acids 6 to 183 (178 residues), 77.1 bits, see alignment E=3.3e-25

Best Hits

Swiss-Prot: 64% identical to QOR2_ECOLI: Quinone oxidoreductase 2 (qorB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 68% identity to pna:Pnap_0622)

MetaCyc: 64% identical to NAD(P)H:quinone oxidoreductase (Escherichia coli K-12 substr. MG1655)
1.6.5.-

Predicted SEED Role

"NADPH:quinone oxidoreductase 2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GSY6 at UniProt or InterPro

Protein Sequence (279 amino acids)

>Pf6N2E2_4112 NADPH:quinone oxidoreductase 2 (Pseudomonas fluorescens FW300-N2E2)
MIAITGASGQLGRLVIQSLLERVPAEQIVALVRDPGKVQDLAARGVVVRTADYNQPATLT
AALKGVDKLLLISSNELGNRAAQHRAVIDAAKAAGVTLLAYTSVLHADTSILGLAAEHRD
TEAALKASGVPHVLLRNGWYSENYLANVPSAVEHGVLLGSAGEGRISSAPRADYAQAAAV
VLTTEGQAGKVYELAGDSSYTLTELAALISQKTGKPVAYQNLPQAEFEAVLISVGLPAGL
AALLADSDAAAAKGALFDESGVLGRLIGRGTTPVSESLS