Protein Info for Pf6N2E2_3980 in Pseudomonas fluorescens FW300-N2E2

Annotation: Type I secretion system, outer membrane component LapE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 19 to 426 (408 residues), 289.2 bits, see alignment E=2.9e-90 PF02321: OEP" amino acids 24 to 215 (192 residues), 98.8 bits, see alignment E=1.8e-32 amino acids 235 to 419 (185 residues), 97.5 bits, see alignment E=4.4e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to pba:PSEBR_a207)

Predicted SEED Role

"Type I secretion system, outer membrane component LapE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165ZIL2 at UniProt or InterPro

Protein Sequence (449 amino acids)

>Pf6N2E2_3980 Type I secretion system, outer membrane component LapE (Pseudomonas fluorescens FW300-N2E2)
MRLHLFKALPFALAASFVQAQTLPQAMQQALDVHPEIQAGVNSRLAADYQLKAAKGGYLP
RVDLAAGYGREGTDSVTTRSGGTNHWETLNRSESSLRLSQMVFDGFATSSEVGRQQATVN
ARAYSLLDASERTGLTVAQVYLDVLTRREFVRLAEENLKSHERIFDQIKLRTSRGVGSGA
DLDQAEARMAQARNNLITEQTNLADAETNYLSAVGQLPDQLERPADFLALLPANLTEARA
QMLENSPVLRSAEADIAAAEQQYEAAKSSFYPRFDAELGRTADNDLDGQNGHNNEWQAML
RMRFNLYAGGSNKADLESKSYLSNQALDIRNNALRQLNEELGLAWNALNNANAQVPVAQQ
YVDRSANVRTAYQKQFSLGERTLLDLLDSENELFSASRRLAEIKNVQLFTQYRIKATMGQ
LLKSQGVVAPLASVVQNDMKPKVQLPGMN