Protein Info for Pf6N2E2_3818 in Pseudomonas fluorescens FW300-N2E2

Annotation: GTP-binding protein TypA/BipA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 606 PF00009: GTP_EFTU" amino acids 4 to 192 (189 residues), 191.1 bits, see alignment E=3.8e-60 TIGR00231: small GTP-binding protein domain" amino acids 5 to 139 (135 residues), 81.3 bits, see alignment E=6.7e-27 TIGR01394: GTP-binding protein TypA/BipA" amino acids 5 to 599 (595 residues), 933.8 bits, see alignment E=3.3e-285 PF01926: MMR_HSR1" amino acids 8 to 129 (122 residues), 26.7 bits, see alignment E=1.3e-09 PF03144: GTP_EFTU_D2" amino acids 219 to 289 (71 residues), 40.7 bits, see alignment E=6.8e-14 PF00679: EFG_C" amino acids 396 to 477 (82 residues), 76.1 bits, see alignment E=4.4e-25 PF21018: BipA_C" amino acids 485 to 592 (108 residues), 154.4 bits, see alignment E=2e-49

Best Hits

Swiss-Prot: 71% identical to TYPA_ECO27: GTP-binding protein TypA/BipA (typA) from Escherichia coli O127:H6 (strain E2348/69 / EPEC)

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to pba:PSEBR_a364)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A1G1 at UniProt or InterPro

Protein Sequence (606 amino acids)

>Pf6N2E2_3818 GTP-binding protein TypA/BipA (Pseudomonas fluorescens FW300-N2E2)
VIENLRNIAIIAHVDHGKTTLVDKLLRQSGTLERNELNDERVMDSNDQEKERGITILAKN
TAINWNGYHINIVDTPGHADFGGEVERVMSMVDSVLLLVDAQDGPMPQTRFVTKKAFEAG
LRPIVVINKVDRPGARPDWVLDQIFDLFDNLGATEEQLDFKVVYASALNGIAGLDHTNMA
EDMTPLYQSIVDDVPAPKVDRDGPFQMQISALDYNSFLGVIGVGRIARGRIKPNTPVVAI
DADGKKRNGRILKLMGHHGLHRIDVEEAAAGDIVCISGFEQLFISDTLCDPLNVEAMKPL
TVDEPTVSMTFQVNDSPFCGKEGKFVTSRNIKERLDKELLYNVALRVEEGDSADKFKVSG
RGELHLSVLIETMRREGFEMGVGRPEVIIRMVDGVKHEPYENVTIDLPEESQGAIMEQMG
LRKGDLTNMVPDGKGRVRLEYNIPARGLIGFRNEFLTLTSGGGILTSIFDRYDVMKSGDM
SGRQNGVLVSVATGKALTYSLETLQARGKLFVEHGQDIYEGQIVGLNSRDNDLGVNPTKG
KKLDNMRASGKDETIALVPPVKFTLEQALEFVQEDELCEVTPKSIRLRKKILGESERTRA
AKKSGN