Protein Info for Pf6N2E2_3460 in Pseudomonas fluorescens FW300-N2E2

Annotation: Exodeoxyribonuclease V beta chain (EC 3.1.11.5)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1229 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR00609: exodeoxyribonuclease V, beta subunit" amino acids 9 to 1211 (1203 residues), 1099.8 bits, see alignment E=0 PF00580: UvrD-helicase" amino acids 11 to 160 (150 residues), 78.5 bits, see alignment E=1.7e-25 amino acids 334 to 445 (112 residues), 89.4 bits, see alignment E=8.5e-29 PF13245: AAA_19" amino acids 18 to 433 (416 residues), 42 bits, see alignment E=2.6e-14 PF13361: UvrD_C" amino acids 704 to 841 (138 residues), 55 bits, see alignment E=2.4e-18 PF12705: PDDEXK_1" amino acids 988 to 1192 (205 residues), 26.7 bits, see alignment E=1.4e-09

Best Hits

KEGG orthology group: K03582, exodeoxyribonuclease V beta subunit [EC: 3.1.11.5] (inferred from 98% identity to pba:PSEBR_a683)

Predicted SEED Role

"Exodeoxyribonuclease V beta chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165ZG08 at UniProt or InterPro

Protein Sequence (1229 amino acids)

>Pf6N2E2_3460 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) (Pseudomonas fluorescens FW300-N2E2)
MSRQTPLALAFPLRGSQLIEASAGTGKTFTISALYLRLVLGHGGPASGFGRELLPPQILV
VTFTDAATKELRERIRTRLAEAARFFRDEIPAPDSLIAALRDEFNAEQWPGCANRLDIAA
QWMDEAAVSTIHSWCQRMLREHAFDSGSLFTQTLETDHSELLGEVLRDYWRLFCYSMQGE
ALNWVRTHWGGPAALLPRVRGLFSSEHGNGDGLEPAELIAAALQERSAALLDLKAPWRQW
AVELLEICQQGVASKSVDGRKMQARYFEPWFQKITAWVDDESLELLDIGTGFTRLTPEGM
AEAWKGEVPNHPGLDAMASLKASLDALPTPDAAVLQHAAQWVGTRFEAEKRRRAEMGFDD
MLLRLDAALQADGGERLASLIREQFPVALIDEFQDTDPVQYRIFESIYRIEDNDPGTGLF
LIGDPKQAIYAFRGADIYTYLRAREATAGRLHTLGTNFRSSHAMVGAVNHIFQKAESRPK
GRGAFLFREPSGENPVPFLSVESQGRKESLQVAGQAVAALNIWHLSSDQPLSGAVYRQSM
AAACASEITALLNGGQSGRDGFTVDGKVLRGVRPADIAILVRDGKEAQAVRDALSARGVR
SVYLSDKDSVFASQEARDLLIWLRACAEPDAERPLRAALASITLNLALTELERLNQDELA
WEARVMQFRGYRTVWRSQGVLPMLRRLLHDFELPQALMARSDGERVLTNLLHLCELLQQA
AGELDGEQALIRHLSEHLALSGQVGEEQILRLESDEQLVKVVTIHKSKGLEYPLVFLPFI
CSTKPVDGSRLPLHYHDEANKAQISLKPTAELIAKADDERLAEDLRLLYVALTRAQHACW
LGVADLKRGSNNRSILHVSALGYLLGGGAPLAESVELRRWLQDLQQGSDAVSYQPMPEAT
DEHYRPPRNEAVLLEPLVPLRKASENWWIASYSALRISESLSEGSDTAPESPQAQKLFDD
ERLDPDAPRETLAVGGDIHRFPRGPNPGTFLHGLLEWAAGEGFSSAPADIEDAIARRCNR
RGWKGWITTLSDWLRHLIKMPMHVGNDQAPVVLEHLSRFQVEMEFWFASHKVDVQKLDQL
VCRFTHGGVARVAAEPVLLNGMFKGFIDLTFEHDGRYYVADYKSNWLGVDDMAYTVPAME
QSILDHRYDLQYVLYLLALHRQLKARLPDYDYDRHVGGALYLFLRGTRSASQGVYFTKPP
RALIEQLDRLFQGASEPKAEPAWVQGELL