Protein Info for Pf6N2E2_3458 in Pseudomonas fluorescens FW300-N2E2

Annotation: Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 PF13538: UvrD_C_2" amino acids 147 to 193 (47 residues), 43.4 bits, see alignment 1.2e-15

Best Hits

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (223 amino acids)

>Pf6N2E2_3458 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) (Pseudomonas fluorescens FW300-N2E2)
VAPQGYRHYLSLLRQRRPSISRPLEDRCWTDWAREVLAAFDEFQLLCAVRKGPWGVEGLN
LRITAALLKARLIDSDHQWYEGRPVLMTRNDYGLGLMNGDIGIALKLPERDGPDAGKQVL
RVAFPRNDGRGGVRFVLPSRLNDVETVYAMTVHKSQGSEFTHTALILPDALNPVLTKELV
YTAITRGKQWFSLIEPRAGVFEEAVRRKVKRLSGLMLELEGDD