Protein Info for Pf6N2E2_322 in Pseudomonas fluorescens FW300-N2E2

Annotation: Transcriptional regulator, LacI family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 PF00356: LacI" amino acids 4 to 48 (45 residues), 63.6 bits, see alignment 2.2e-21 PF00532: Peripla_BP_1" amino acids 61 to 312 (252 residues), 116.1 bits, see alignment E=4.2e-37 PF13377: Peripla_BP_3" amino acids 168 to 328 (161 residues), 150.2 bits, see alignment E=1.2e-47

Best Hits

KEGG orthology group: K05499, LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG (inferred from 97% identity to pba:PSEBR_a3537)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165YS09 at UniProt or InterPro

Protein Sequence (332 amino acids)

>Pf6N2E2_322 Transcriptional regulator, LacI family (Pseudomonas fluorescens FW300-N2E2)
LSNIREVARLAGVSVATVSRTLKSPERVLPETRDKVNAAVEQAGYRPNLMAVQFRSRRTG
NLVILVPAIANTFFARVISGAQQAAQAAGYRLLLCDTRGRAQIEREFAALVYAHQADGVI
QLRASDPFESMPAGVESLPLVNACEVVKNAPYPTISLDNRAAAQAMTEHLIGLGHRRIGI
IKGPRSSPLTLDRVAGYQDALSQAGIAVDPSLICHGDFTLKAGDDGAGAMLALADRPSAL
FCENDEMAIGALRRIKQMGLRVPEDISLVGFDDIPFAAYCDPPLTTISQPAEIFGEKAVQ
MLIALIEKKPIAERHVVLPFELTVRGSTAPLA