Protein Info for Pf6N2E2_2903 in Pseudomonas fluorescens FW300-N2E2

Annotation: Heme oxygenase HemO, associated with heme uptake

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 PF01126: Heme_oxygenase" amino acids 10 to 188 (179 residues), 73.8 bits, see alignment E=9.1e-25

Best Hits

KEGG orthology group: None (inferred from 94% identity to pba:PSEBR_a1203)

Predicted SEED Role

"Heme oxygenase HemO, associated with heme uptake" in subsystem Heme, hemin uptake and utilization systems in GramPositives or Hemin transport system or Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZWJ9 at UniProt or InterPro

Protein Sequence (196 amino acids)

>Pf6N2E2_2903 Heme oxygenase HemO, associated with heme uptake (Pseudomonas fluorescens FW300-N2E2)
MNTLRPASRSQRLNQITHEPHSKLDALVKAHAPFETPASFARFVVAQYLFQSELVALYND
AELSALIPDLPARCRADAAKADLADLDTEVPAPVAGAVNKPTQAEALGWLFVSEGSKLGA
AFLIKRAVGLGLSETFGARHLAEPAGGRAEGWKTFTRTLDSLAFTEQQEAEADKGALDAF
NRFTVLLEQAYAAELA