Protein Info for Pf6N2E2_2775 in Pseudomonas fluorescens FW300-N2E2

Annotation: Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 355 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR03427: ABC transporter periplasmic binding protein, urea carboxylase region" amino acids 27 to 355 (329 residues), 577.6 bits, see alignment E=3.8e-178 PF13379: NMT1_2" amino acids 53 to 255 (203 residues), 29.5 bits, see alignment E=6.6e-11 PF09084: NMT1" amino acids 57 to 237 (181 residues), 36 bits, see alignment E=7.4e-13

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 98% identity to pba:PSEBR_a1323)

Predicted SEED Role

"Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165ZAZ3 at UniProt or InterPro

Protein Sequence (355 amino acids)

>Pf6N2E2_2775 Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein (Pseudomonas fluorescens FW300-N2E2)
MFKLRLSALLLAALSALVSFSSAAAQKDHFSVCWTIYAGWMPWEYAGSQGIVDKWAKKYG
IKIDVVQLNDYVESINQYTAGQFDGCTMTNMDALTIPAAGGVDSTALIVSDFSNGNDGIV
LKGEGKKVTDLKGMDVNLVELSVSHYLLARALDSVGLAEKDLKVVNTSDADISAAFNTDQ
VKAVTTWNPMLSDIKAQPGVSEVFNSSQVPGEIMDMMVVNTQTLQDNPALGKALTGAWFE
VVALMNAKNAASKTALEHMAKASGTDLAGFQAQLDTTKLFATPKEALGFATSEQLPATMG
KVANFSFQHGLLGEGAKDANAVGMAFANGVTRGDKANLKLRFDPTYVQLAADAKL